Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 6/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12594543 | 0.92 | CNR2 (0.41) | CYP2C8CYP2C9CNR2RARARARB | |
| SCHEMBL2606549 | 0.88 | PDK2 (0.43) | CYP2C8CYP2C9CNR2RXRARARA | |
| SCHEMBL353237 | 0.85 | CYP2C8 (0.40) | CYP2C8CYP2C9RXRARARARARB | |
| SCHEMBL2606548 | 0.83 | PDK2 (0.43) | CYP2C8CYP2C9CNR2RXRARARA | |
| SCHEMBL13493204 | 0.82 | CYP2C8 (0.31) | CYP2C8CYP2C9PDK2 | |
| SCHEMBL14365749 | 0.75 | CYP2C8 (0.35) | CYP2C8CYP2C9RXRARARARARB | |
| SCHEMBL11914359 | 0.74 | CNR2 (0.41) | CYP2C8CYP2C9CNR2RXRARARA | |
| SCHEMBL11914299 | 0.70 | PDK2 (0.39) | CYP2C8CYP2C9CNR2RXRARARA | |
| SCHEMBL12594542 | 0.69 | PDK2 (0.45) | CYP2C8CYP2C9CNR2RXRARARA | |
| SCHEMBL10010220 | 0.69 | PDK2 (0.40) | CNR2RXRARARBRARGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150228905-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | US | disclosed |
| US-20150228905-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | US | disclosed |
| US-9051233-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-9051233-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-20110114889-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110114889-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110114889-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, EED, EML4 | CYP2C8 1822/4885CYP2C9 160/4885CNR2 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.