Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606548 | 0.91 | PDK2 (0.43) | PDK2CNR2CYP2C8CYP2C9ATM | |
| SCHEMBL12594529 | 0.88 | CYP2C8 (0.43) | PDK2CNR2CYP2C8CYP2C9ATM | |
| SCHEMBL353237 | 0.83 | CYP2C8 (0.40) | CYP2C8CYP2C9ATMTDP1L3MBTL1 | |
| SCHEMBL12594543 | 0.82 | CNR2 (0.41) | PDK2CNR2CYP2C8CYP2C9ATM | |
| SCHEMBL11914359 | 0.82 | CNR2 (0.41) | PDK2CNR2CYP2C8CYP2C9ATM | |
| SCHEMBL16271526 | 0.76 | PDK2 (0.52) | PDK2CNR2ATMTDP1L3MBTL1 | |
| SCHEMBL25011572 | 0.75 | PDK2 (0.62) | PDK2CNR2CYP2C8CYP2C9ATM | |
| SCHEMBL10227419 | 0.75 | CYP2C8 (0.46) | PDK2CNR2CYP2C8CYP2C9ATM | |
| SCHEMBL11914299 | 0.74 | PDK2 (0.39) | PDK2CNR2CYP2C8CYP2C9RXRA | |
| SCHEMBL14365749 | 0.74 | CYP2C8 (0.35) | CYP2C8CYP2C9RXRARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241763-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-08-14 | — | — | US | disclosed |
| US-8241763-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-08-14 | — | — | US | disclosed |
| EP-2038370-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SLC26A3, SLCO4C1 | PDK2 2586/4885CNR2 3911/4885CYP2C8 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.