Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905442 | 0.77 | — | — | |
| SCHEMBL537763 | 0.74 | USP2 (0.35) | USP2TSHRKDM4EALDH1A1LMNA | |
| Methane SCHEMBL7131370 | 0.70 | CA2 (0.38) | TSHR | |
| SCHEMBL2057691 | 0.70 | USP2 (0.32) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2057217 | 0.69 | ALDH1A1 (0.36) | USP2TSHRALDH1A1 | |
| SCHEMBL7715534 | 0.67 | — | — | |
| SCHEMBL2059582 | 0.67 | — | — | |
| SCHEMBL2058251 | 0.67 | CA1 (0.33) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL30018224 | 0.65 | USP2 (0.44) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6070723 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190870-A1 | FGFR3 INHIBITOR COMPOUNDS | LOXO ONCOLOGY, INC. | 2024-06-13 | — | — | US | disclosed |
| US-11878976-B2 | FGFR3 inhibitor compounds | ELI LILLY AND COMPANY (US) | 2024-01-23 | — | — | US | disclosed |
| US-20230095122-A1 | FGFR3 INHIBITOR COMPOUNDS | LOXO ONCOLOGY, INC. | 2023-03-30 | — | — | US | disclosed |
| US-9259476-B2 | Monophosphorylated lipid A derivatives | WAYNE STATE UNIVERSITY (US) | 2016-02-16 | — | — | US | disclosed |
| US-20140356367-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | WAYNE STATE UNIVERSITY | 2014-12-04 | — | — | US | disclosed |
| US-8809285-B2 | Monophosphorylated lipid A derivatives | WAYNE STATE UNIVERSITY (US) | 2014-08-19 | — | — | US | disclosed |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-07-26 | — | — | US | disclosed |
| WO-2011014771-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | WAYNE STATE UNIVERSITY (US) | 2011-02-03 | — | — | WO | disclosed |
| US-6787612-B1 | PRODUCING SUCH AS HYDRAZYL-CARBONYL-AMINO METHYLATED POLYSTYRENE; MINIMIZES SOLUTION-PHASE SYNTHETIC STEPS IN SOLID-PHASE PEPTIDE OR PEPTIDE ANALOG SYNTHESIS | DENDREON CORPORATION | 2004-09-07 | — | — | US | disclosed |
| EP-1100812-A2 | RESIN DERIVATIZATION METHOD AND USES THEREOF | CORVAS INTERNATIONAL, INC. (US) | 2001-05-23 | — | — | EP | disclosed |
| EP-1100782-A1 | AMINO-ALDEHYDE SOLID SUPPORT, LINKER THEREFOR AND METHODS OF PREPARATION AND USE THEREOF | CORVAS INTERNATIONAL, INC. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000005208-A9 | AMINO-ALDEHYDE SOLID SUPPORT, LINKER THEREFOR AND METHODS OF PREPARATION AND USE THEREOF | CORVAS INT INC (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000005243-A2 | RESIN DERIVATIZATION METHOD AND USES THEREOF | CORVAS INTERNATIONAL INC. (US) | 2000-02-03 | — | — | WO | disclosed |
| WO-2000005208-A1 | AMINO-ALDEHYDE SOLID SUPPORT, LINKER THEREFOR AND METHODS OF PREPARATION AND USE THEREOF | CORVAS INTERNATIONAL INC. (US) | 2000-02-03 | — | — | WO | disclosed |
| EP-0591256-A1 | METHODS FOR THE SYNTHESIS OF MONOFUCOSYLATED OLIGOSACCHARIDES TERMINATING IN DI-N-ACETYLLACTOSAMINYL STRUCTURES | GLYCOMED INCORPORATED (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1992022662-A1 | METHODS FOR THE SYNTHESIS OF MONOFUCOSYLATED OLIGOSACCHARIDES TERMINATING IN DI-N-ACETYLLACTOSAMINYL STRUCTURES | ALBERTA RESEARCH COUNCIL (CA) | 1992-12-23 | — | — | WO | disclosed |
| EP-0399645-A2 | Tetrahydropyranyl derivatives, process for their preparation and pharmaceutical or veterinary compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0376724-A2 | Cephalosporin compounds | TANABE SEIYAKU CO., LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140356367-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | SGMS1, PCYT1A, PHOSPHO1 | USP2 4115/4885TSHR 3233/4885KDM4E 2273/4885 |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | SGMS1, PCYT1A, PHOSPHO1 | USP2 4115/4885TSHR 3233/4885KDM4E 2273/4885 |
| US-11878976-B2 | FGFR3 inhibitor compounds | FGFR3, FGFR1, FGFR2 | USP2 3697/4885TSHR 3864/4885KDM4E 1944/4885 |
| US-20240190870-A1 | FGFR3 INHIBITOR COMPOUNDS | FGFR3, FGFR1, FGFR2 | USP2 3697/4885TSHR 3864/4885KDM4E 1944/4885 |
| US-20230095122-A1 | FGFR3 INHIBITOR COMPOUNDS | FGFR3, FGFR1, FGFR2 | USP2 3697/4885TSHR 3864/4885KDM4E 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.