Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12596359 | 0.77 | GPR119 (0.65) | GPR119 | |
| SCHEMBL1128256 | 0.77 | CYP3A4 (0.52) | GPR119CYP2C9KCNH2PIK3CD | |
| SCHEMBL14927795 | 0.75 | GPR119 (0.51) | GPR119CYP2C9KCNH2 | |
| SCHEMBL12596752 | 0.75 | GPR119 (0.57) | GPR119CYP2C9KCNH2 | |
| SCHEMBL514777 | 0.74 | GPR119 (0.43) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390152 | 0.73 | GPR119 (0.74) | GPR119CYP2C9KCNH2 | |
| SCHEMBL14930835 | 0.72 | GPR119 (0.65) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1128363 | 0.71 | GPR119 (0.66) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1128654 | 0.71 | CYP3A4 (0.51) | GPR119CYP2C9KCNH2 | |
| SCHEMBL12596500 | 0.70 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118286-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS GPCR MODULATORS | SCHERING CORPORATION | 2011-05-19 | — | — | US | disclosed |
| US-20110118286-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS GPCR MODULATORS | SCHERING CORPORATION | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118286-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS GPCR MODULATORS | GPR119, GCGR, GPR35 | GPR119 1/4885CYP2C9 709/4885KCNH2 2035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.