Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12940717 | 0.87 | LIPG (0.45) | LIPGSMN1; SMN2MTNR1AMTNR1BAPLNR | |
| SCHEMBL12597433 | 0.79 | MTNR1A (0.41) | SMN1; SMN2MTNR1AMTNR1BAPLNRHDAC6 | |
| SCHEMBL12597246 | 0.76 | CYSLTR1 (0.34) | — | |
| SCHEMBL12940754 | 0.69 | LIPG (0.48) | LIPG | |
| SCHEMBL12941831 | 0.69 | MTNR1A (0.41) | SMN1; SMN2MTNR1AMTNR1BAPLNRHDAC6 | |
| SCHEMBL12597249 | 0.69 | CYSLTR2 (0.44) | — | |
| SCHEMBL12596664 | 0.68 | LIPG (0.45) | LIPGMTNR1AMTNR1B | |
| SCHEMBL12597437 | 0.68 | MEN1 (0.49) | LIPGSMN1; SMN2MTNR1AMTNR1BHDAC6 | |
| SCHEMBL12940876 | 0.68 | LIPG (0.57) | LIPG | |
| SCHEMBL12597422 | 0.68 | LIPG (0.67) | LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011074560-A1 | OXADIAZOLE DERIVATIVE HAVING ENDOTHELIAL LIPASE INHIBITORY ACTIVITY | 塩野義製薬株式会社 (JP) | 2011-06-23 | — | — | WO | disclosed |