Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA6 | P17658 | 9/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 9/20 | 0.41 |
| ▸ | KCNA4 | P22459 | 9/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12598175 | 0.78 | KCNA6 (0.42) | KCNA6KCNA3KCNA4KCNA5NT5E | |
| SCHEMBL12597863 | 0.78 | CBLB (0.39) | CBLB | |
| Oroidin SCHEMBL14536687 | 0.77 | KCNA6 (0.65) | KCNA6KCNA3KCNA4KCNA5NT5E | |
| Hydrochloric Acid SCHEMBL1518082 | 0.77 | CBLB (0.39) | CBLB | |
| Oroidin SCHEMBL28891358 | 0.77 | KCNA6 (0.65) | KCNA6KCNA3KCNA4KCNA5NT5E | |
| Oroidin SCHEMBL12597862 | 0.77 | KCNA6 (0.65) | KCNA6KCNA3KCNA4KCNA5NT5E | |
| SCHEMBL13036735 | 0.77 | KCNA6 (0.67) | KCNA6KCNA3KCNA4KCNA5NT5E | |
| Dihydrosventrin SCHEMBL12559819 | 0.76 | CBLB (0.38) | CBLB | |
| SCHEMBL12597864 | 0.75 | CBLB (0.38) | CBLB | |
| Dihydrosventrin SCHEMBL1518647 | 0.75 | CBLB (0.38) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084423-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| US-8653124-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20110150819-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-06-23 | — | — | US | disclosed |
| US-7906544-B2 | Dentifrices; stents; catheters; grafts | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080181923-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181923-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | KCNA6 2338/4885KCNA3 2208/4885KCNA4 3513/4885 |
| US-20110150819-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | KCNA6 2338/4885KCNA3 2208/4885KCNA4 3513/4885 |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | KCNA6 2338/4885KCNA3 2208/4885KCNA4 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.