Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1518082 | 0.99 | CBLB (0.39) | CBLBMAPTNPC1ALOX15RAB9A | |
| Dihydrosventrin SCHEMBL12559819 | 0.93 | CBLB (0.38) | CBLBMAPTNPC1ALOX15RAB9A | |
| Dihydrosventrin SCHEMBL1518647 | 0.92 | CBLB (0.38) | CBLBMAPTNPC1ALOX15RAB9A | |
| SCHEMBL12597864 | 0.92 | CBLB (0.38) | CBLBMAPTNPC1ALOX15RAB9A | |
| Hydrochloric Acid SCHEMBL1518079 | 0.91 | CBLB (0.37) | CBLBMAPTNPC1ALOX15RAB9A | |
| SCHEMBL12648616 | 0.84 | HDAC1 (0.39) | CBLBHDAC1 | |
| Hydrochloric Acid SCHEMBL1523923 | 0.84 | HDAC1 (0.39) | CBLBHDAC1 | |
| SCHEMBL13667359 | 0.81 | HDAC1 (0.34) | CBLBMAPTNPC1ALOX15RAB9A | |
| SCHEMBL12597895 | 0.81 | MAPT (0.36) | CBLBMAPTNPC1ALOX15RAB9A | |
| SCHEMBL13803814 | 0.81 | MAPT (0.34) | MAPTNPC1ALOX15RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084423-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-8927029-B2 | Inhibition of biofilms in plants with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140079808-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-8653124-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20120328577-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | MELANDER CHRISTIAN (US) | 2012-12-27 | — | — | US | disclosed |
| US-8278340-B2 | Inhibition of biofilms in plants with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278340-B2 | Inhibition of biofilms in plants with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-10-02 | — | — | US | disclosed |
| US-20110150819-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-06-23 | — | — | US | disclosed |
| US-7906544-B2 | Dentifrices; stents; catheters; grafts | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-15 | — | — | US | disclosed |
| US-20090143230-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090143230-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-04 | — | — | US | disclosed |
| WO-2008094479-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-08-07 | — | — | WO | disclosed |
| US-20080181923-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY | 2008-07-31 | — | — | US | disclosed |
| US-20080181923-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181923-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | CBLB 2344/4885MAPT 3627/4885NPC1 4428/4885 |
| US-20140079808-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | ITPA, SOD1, ICMT | CBLB 440/4885MAPT 697/4885NPC1 2667/4885 |
| US-20120328577-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | ITPA, SOD1, ICMT | CBLB 440/4885MAPT 697/4885NPC1 2667/4885 |
| US-20110150819-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | CBLB 2344/4885MAPT 3627/4885NPC1 4428/4885 |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | CBLB 2344/4885MAPT 3627/4885NPC1 4428/4885 |
| US-20090143230-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | ITPA, SOD1, ICMT | CBLB 440/4885MAPT 697/4885NPC1 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.