SCHEMBL12600802

SCHEMBL12600802

COC(=O)C1(OC(C)=O)CC(OC(C)=O)C(NC(C)=O)C([C@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O)O1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 2/20 0.38
▸ TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15343657 1.00 NANP (0.38) NANPTDP1
SCHEMBL29259492 1.00 NANP (0.38) NANPTDP1
SCHEMBL15343918 1.00 NANP (0.38) NANPTDP1
SCHEMBL30946520 1.00 NANP (0.38) NANPTDP1
SCHEMBL126553 1.00 NANP (0.38) NANPTDP1
SCHEMBL24630164 1.00 NANP (0.38) NANPTDP1
SCHEMBL15279194 0.92 NANP (0.36) NANPTDP1
SCHEMBL25426120 0.92 NANP (0.36) NANPTDP1
SCHEMBL20495386 0.92 NANP (0.36) NANPTDP1
SCHEMBL25426117 0.92 NANP (0.36) NANPTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140356367-A1 MONOPHOSPHORYLATED LIPID A DERIVATIVES WAYNE STATE UNIVERSITY 2014-12-04 — — US disclosed
US-7943330-B2 Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins ACADEMIA SINICA (TW) 2011-05-17 — — US disclosed
WO-2011014771-A1 MONOPHOSPHORYLATED LIPID A DERIVATIVES WAYNE STATE UNIVERSITY (US) 2011-02-03 — — WO disclosed
US-20080299595-A1 Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins ACADEMIA SINICA (TW) 2008-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140356367-A1 MONOPHOSPHORYLATED LIPID A DERIVATIVES SGMS1, PCYT1A, PHOSPHO1 NANP 95/4885TDP1 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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