SCHEMBL24630164

SCHEMBL24630164

COC(=O)[C@@]1(OC(C)=O)C[C@H](OC(C)=O)[C@@H](NC(C)=O)[C@H]([C@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O)O1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 2/20 0.38
▸ TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15343657 1.00 NANP (0.38) NANPTDP1
SCHEMBL29259492 1.00 NANP (0.38) NANPTDP1
SCHEMBL12600802 1.00 NANP (0.38) NANPTDP1
SCHEMBL15343918 1.00 NANP (0.38) NANPTDP1
SCHEMBL30946520 1.00 NANP (0.38) NANPTDP1
SCHEMBL126553 1.00 NANP (0.38) NANPTDP1
SCHEMBL15279194 0.92 NANP (0.36) NANPTDP1
SCHEMBL25426120 0.92 NANP (0.36) NANPTDP1
SCHEMBL20495386 0.92 NANP (0.36) NANPTDP1
SCHEMBL25426117 0.92 NANP (0.36) NANPTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 — — EP disclosed
EP-4554622-A2 AUTOANTIGENS ENGINEERED TO SUPPRESS AUTOIMMUNE RESPONSE Osprey Biopharmaceuticals, Inc. (US) 2025-05-21 — — EP disclosed
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF ADAXION THERAPEUTICS, INC. 2025-04-24 — — US disclosed
WO-2025076427-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF OSPREY BIOPHARMACEUTICALS, INC. (US) 2025-04-10 — — WO disclosed
US-20250064941-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF ADAXION THERAPEUTICS, INC. 2025-02-27 — — US disclosed
WO-2024259007-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF OSPREY BIOPHARMACEUTICALS, INC. (US) 2024-12-19 — — WO disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
WO-2024015872-A2 AUTOANTIGENS ENGINEERED TO SUPPRESS AUTOIMMUNE RESPONSE OSPREY BIOPHARMACEUTICALS, INC. (US) 2024-01-18 — — WO disclosed
WO-2024015872-A2 AUTOANTIGENS ENGINEERED TO SUPPRESS AUTOIMMUNE RESPONSE OSPREY BIOPHARMACEUTICALS, INC. (US) 2024-01-18 — — WO disclosed
EP-4274582-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS Osprey Biopharmaceuticals, Inc. (US) 2023-11-15 — — EP disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF SIGLEC7, SIGLEC9, SELPLG NANP 357/4885TDP1 3848/4885
US-20250064941-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF SIGLEC7, SIGLEC9, CD2BP2 NANP 503/4885TDP1 2616/4885
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 NANP 1968/4885TDP1 2271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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