SCHEMBL126553

SCHEMBL126553

COC(=O)[C@]1(OC(C)=O)C[C@H](OC(C)=O)[C@@H](NC(C)=O)[C@H]([C@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O)O1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 2/20 0.38
▸ TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15343657 1.00 NANP (0.38) NANPTDP1
SCHEMBL29259492 1.00 NANP (0.38) NANPTDP1
SCHEMBL12600802 1.00 NANP (0.38) NANPTDP1
SCHEMBL15343918 1.00 NANP (0.38) NANPTDP1
SCHEMBL30946520 1.00 NANP (0.38) NANPTDP1
SCHEMBL24630164 1.00 NANP (0.38) NANPTDP1
SCHEMBL15279194 0.92 NANP (0.36) NANPTDP1
SCHEMBL25426120 0.92 NANP (0.36) NANPTDP1
SCHEMBL20495386 0.92 NANP (0.36) NANPTDP1
SCHEMBL25426117 0.92 NANP (0.36) NANPTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144849-B2 Polishing composition and polishing method using the same FUJIMI INCORPORATED (JP) 2018-12-04 — — US disclosed
US-20160129122-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. 2016-05-12 — — US disclosed
US-20160129122-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. 2016-05-12 — — US disclosed
US-9181281-B2 Prodrugs of neuraminidase inhibitors SineVir Therapeutics LLC (US) 2015-11-10 — — US disclosed
US-20140288025-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2014-09-25 — — US disclosed
US-20140288025-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2014-09-25 — — US disclosed
US-20140155350-A1 Prodrugs of Neuraminidase Inhibitors SineVir Therapeutics LLC (US) 2014-06-05 — — US disclosed
US-20130244966-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2013-09-19 — — US disclosed
US-20130244966-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2013-09-19 — — US disclosed
WO-2013090420-A2 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2013-06-20 — — WO disclosed
US-20120264928-A1 THERAPEUTIC PHARMACEUTICAL AGENT FOR DISEASES ASSOCIATED WITH DECREASE IN FUNCTION OF GNE PROTEIN, FOOD COMPOSITION, AND FOOD ADDITIVE JAPAN HEALTH SCIENCES FOUNDATION (JP) 2012-10-18 — — US disclosed
US-20120058937-A9 Prodrugs of Neuraminidase Inhibitors TSRL, INC. (US) 2012-03-08 — — US disclosed
US-20110160127-A1 Prodrugs of Neuraminidase Inhibitors TSRL, INC. (US) 2011-06-30 — — US disclosed
US-20100301014-A1 Polishing Composition and Polishing Method Using the Same FUJIMI INCORPORATED (JP) 2010-12-02 — — US disclosed
EP-2237311-A1 POLISHING COMPOSITION AND POLISHING METHOD USING THE SAME FUJIMI INCORPORATED (JP) 2010-10-06 — — EP disclosed
US-4229441-A Immunologic adjuvant MERCK & CO., INC. (US) 1980-10-21 — — US disclosed
EP-0012083-A1 Immunologic adjuvant, process for preparation and vaccine containing such adjuvant MERCK & CO. INC. (US) 1980-06-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130244966-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES FABP1, FABP2, HAVCR2 NANP 436/4885TDP1 3986/4885
US-20140288025-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES FABP1, FABP2, HAVCR2 NANP 436/4885TDP1 3986/4885
US-20110160127-A1 Prodrugs of Neuraminidase Inhibitors NEU1, ANPEP, NEU4 NANP 14/4885TDP1 1402/4885
US-20120058937-A9 Prodrugs of Neuraminidase Inhibitors NEU1, ANPEP, NEU4 NANP 14/4885TDP1 1402/4885
US-20120264928-A1 THERAPEUTIC PHARMACEUTICAL AGENT FOR DISEASES ASSOCIATED WITH DECREASE IN FUNCTION OF GNE PROTEIN, FOOD COMPOSITION, AND FOOD ADDITIVE GNE, ENGASE, GNPDA1 NANP 27/4885TDP1 4426/4885
US-20160129122-A1 FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES FABP1, FABP2, HAVCR2 NANP 436/4885TDP1 3986/4885
US-20140155350-A1 Prodrugs of Neuraminidase Inhibitors NEU1, ANPEP, NEU4 NANP 14/4885TDP1 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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