Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.37 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GGH | Q92820 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046561 | 0.85 | KMT2A (0.47) | KMT2AFOLH1RIMKLANAALAD2CA1 | |
| SCHEMBL2920459 | 0.85 | KMT2A (0.47) | KMT2AFOLH1RIMKLANAALAD2CA1 | |
| SCHEMBL702004 | 0.80 | FOLH1 (0.57) | FOLH1RIMKLANAALAD2GGH | |
| SCHEMBL702003 | 0.80 | FOLH1 (0.57) | FOLH1RIMKLANAALAD2GGH | |
| SCHEMBL15935963 | 0.80 | FOLH1 (0.57) | FOLH1RIMKLANAALAD2GGH | |
| SCHEMBL28883926 | 0.79 | FOLH1 (0.55) | FOLH1RIMKLANAALAD2GGH | |
| SCHEMBL28525595 | 0.77 | KMT2A (0.40) | KMT2AFOLH1RIMKLANAALAD2CA1 | |
| SCHEMBL12601703 | 0.77 | KMT2A (0.40) | KMT2AFOLH1RIMKLANAALAD2CA1 | |
| SCHEMBL17369687 | 0.74 | KMT2A (0.38) | KMT2AFOLH1RIMKLANAALAD2CA1 | |
| SCHEMBL27291810 | 0.74 | SLC1A1 (0.45) | KMT2AFOLH1RIMKLANAALAD2GGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883645-B1 | DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC (CA) | 2011-06-29 | — | — | EP | disclosed |