Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | GGH | Q92820 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601703 | 0.80 | KMT2A (0.40) | KMT2AFOLH1NAALAD2RIMKLAGAA | |
| SCHEMBL30962435 | 0.79 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL12601436 | 0.77 | KMT2A (0.38) | KMT2AFOLH1NAALAD2RIMKLAGAA | |
| SCHEMBL17369687 | 0.77 | KMT2A (0.38) | KMT2AFOLH1NAALAD2RIMKLAGAA | |
| SCHEMBL20381105 | 0.76 | KMT2A (0.37) | KMT2AFOLH1NAALAD2RIMKLAGAA | |
| SCHEMBL21231862 | 0.75 | FOLH1 (0.42) | FOLH1NAALAD2RIMKLAGGHALOX15 | |
| SCHEMBL10072709 | 0.74 | FOLH1 (0.52) | KMT2AFOLH1NAALAD2RIMKLAGAA | |
| SCHEMBL15764804 | 0.73 | ALDH1A1 (0.46) | KMT2AFOLH1NAALAD2RIMKLACA1 | |
| SCHEMBL12601003 | 0.72 | CYP1A2 (0.60) | KMT2ANAALAD2ALOX15BLMPMP22 | |
| SCHEMBL18703772 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311980-B | G protein-coupled receptor (GPCR) modulation by emilienone (IMIPRIDONES) | 昂克希尔迪克斯有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-113149985-A | Hexahydroimidazopyridopyrimidinones, analogues and salts thereof, and therapeutic uses thereof | 昂克希尔迪克斯有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107427516-B | 7-benzyl-4- (2-methylbenzyl) -2,4,6,7,8, 9-hexahydroimidazo [1,2-a ] pyrido [3,4-E ] pyrimidin-5 (1H) -ones, analogs thereof, and salts thereof, and methods of their use in therapy | 昂克希尔迪克斯有限公司 | 2021-02-26 | — | — | CN | disclosed |