Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.57 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.57 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.57 |
| ▸ | GGH | Q92820 | 1/20 | 0.48 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935963 | 1.00 | FOLH1 (0.57) | FOLH1NAALAD2RIMKLAGGHTET2 | |
| SCHEMBL702003 | 1.00 | FOLH1 (0.57) | FOLH1NAALAD2RIMKLAGGHTET2 | |
| SCHEMBL28883926 | 0.98 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGHTET2 | |
| SCHEMBL10699563 | 0.86 | FOLH1 (0.45) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18583123 | 0.84 | LMNA (0.44) | FOLH1NAALAD2RIMKLA | |
| Aniline SCHEMBL27955361 | 0.83 | NAALAD2 (0.48) | FOLH1NAALAD2RIMKLAGGH | |
| Aniline SCHEMBL27955360 | 0.83 | NAALAD2 (0.48) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL7046561 | 0.83 | KMT2A (0.47) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL2920459 | 0.83 | KMT2A (0.47) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL2923058 | 0.83 | FOLH1 (0.44) | FOLH1NAALAD2RIMKLAGGHTET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230405091-A1 | METHODS OF MODULATING GASTROINTESTINAL METABOLITES | DSM IP ASSETS B.V. (NL) | 2023-12-21 | — | — | US | claimed |
| EP-4228424-A1 | METHODS OF MODULATING GASTROINTESTINAL METABOLITES | DSM IP Assets B.V. (NL) | 2023-08-23 | — | — | EP | claimed |
| CN-116390651-A | Methods of modulating gastrointestinal metabolites | 帝斯曼知识产权资产管理有限公司 | 2023-07-04 | — | — | CN | claimed |
| US-20230200412-A1 | METHODS OF MODULATING GASTROINTESTINAL MICROBIAL METABOLIC PATHWAYS AND METABOLITES | DSM IP ASSETS B.V. (NL) | 2023-06-29 | — | — | US | claimed |
| CN-116267786-A | Method for improving summer synchronous estrus-timing insemination effect of buffalo | 安徽科技学院 | 2023-06-23 | — | — | CN | claimed |
| EP-4118090-A1 | METHODS OF MODULATING GASTROINTESTINAL MICROBIAL METABOLIC PATHWAYS AND METABOLITES | DSM IP Assets B.V. (NL) | 2023-01-18 | — | — | EP | claimed |
| CN-115551873-A | Methods for modulating gastrointestinal microbial metabolic pathways and metabolites | 帝斯曼知识产权资产管理有限公司 | 2022-12-30 | — | — | CN | claimed |
| WO-2022079238-A1 | METHODS OF MODULATING GASTROINTESTINAL METABOLITES | DSM IP ASSETS B.V. (NL) | 2022-04-21 | — | — | WO | claimed |
| WO-2021183896-A1 | METHODS OF MODULATING GASTROINTESTINAL MICROBIAL METABOLIC PATHWAYS AND METABOLITES | DSM IP ASSETS, B.V. (NL) | 2021-09-16 | — | — | WO | claimed |
| CN-110368132-B | Treatment method for improving synchronous estrus-timing insemination effect of dairy cows in summer | 华中农业大学 | 2020-09-15 | — | — | CN | claimed |
| EP-1974047-B1 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDRO-PTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2010-09-01 | — | — | EP | claimed |
| EP-1974047-A2 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDRO-PTEROIC ACID AND DERIVATIVES THEREOF | Cerbios-Pharma S.A. (CH) | 2008-10-01 | — | — | EP | claimed |
| WO-2007082402-A2 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDROPTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS-PHARMA S.A. (CH) | 2007-07-26 | — | — | WO | claimed |
| CN-121428037-A | Method for synthesizing levofolinic acid based on enzymatic tandem reaction | 浙江工业大学 | 2026-01-30 | — | — | CN | disclosed |
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | OREGON STATE UNIVERSITY (US) | 2026-01-27 | — | — | US | disclosed |
| CN-119343061-A | Pharmaceutical and nutraceutical compositions containing amino acid combinations and their use in diseases characterized by lipid accumulation in tissues | 欧罗卡特基金会 | 2025-01-21 | — | — | CN | disclosed |
| CN-1032858-C | Methylamino pterin derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1996-09-25 | — | — | CN | disclosed |
| CN-1059725-A | Novel methotrexate derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1992-03-25 | — | — | CN | disclosed |
| EP-0388456-A1 | 8,10-DIDEAZATETRAHYDROFOLIC ACID DERIVATIVES | SRI INTERNATIONAL (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1990002745-A1 | 8,10-DIDEAZATETRAHYDROFOLIC ACID DERIVATIVES | SRI INTERNATIONAL (US) | 1990-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | MT-CO1, MT-CO2, PC | FOLH1 3243/4885NAALAD2 4441/4885RIMKLA 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.