Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775998 | 0.83 | AR (0.40) | NOS3NOS1NOS2CTSBAR | |
| SCHEMBL1775240 | 0.83 | AR (0.40) | NOS3NOS1NOS2CTSBAR | |
| SCHEMBL1775972 | 0.83 | AR (0.40) | NOS3NOS1NOS2CTSBAR | |
| SCHEMBL1775056 | 0.80 | PDE4B (0.46) | — | |
| SCHEMBL1775041 | 0.80 | PDE4B (0.46) | — | |
| SCHEMBL1776107 | 0.80 | AR (0.42) | CTSBARSCDGAATDP1 | |
| SCHEMBL30820471 | 0.77 | KDM4E (0.41) | HTR2CHTR2BHTR6SLC6A4 | |
| SCHEMBL12601553 | 0.77 | NOS3 (0.64) | NOS3NOS1NOS2CHRM4CHRM5 | |
| SCHEMBL28552934 | 0.75 | ALDH1A1 (0.43) | HTR2CHTR2BSCDHTR6 | |
| SCHEMBL30792090 | 0.75 | NOS3 (0.38) | NOS3NOS1NOS2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | disclosed |