Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655731 | 0.83 | BTK (0.54) | BTKBRD4 | |
| SCHEMBL3655728 | 0.81 | BTK (0.53) | BTKBRD4 | |
| SCHEMBL104029 | 0.80 | BTK (0.51) | BTK | |
| SCHEMBL103964 | 0.80 | BTK (0.81) | BTK | |
| SCHEMBL106046 | 0.79 | BTK (0.64) | BTK | |
| SCHEMBL105185 | 0.79 | BTK (0.71) | BTK | |
| SCHEMBL103127 | 0.78 | BTK (0.67) | BTK | |
| SCHEMBL105874 | 0.77 | BTK (0.54) | BTK | |
| SCHEMBL108970 | 0.77 | BTK (0.59) | BTK | |
| SCHEMBL103347 | 0.76 | BTK (0.57) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943618-B2 | Btk protein kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090105209-A1 | BTK protein kinase inhibitors | ROCHE PALO ALTO LLC | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105209-A1 | BTK protein kinase inhibitors | BTK, SYK, LYN | BTK 1/4885BRD4 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.