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Sugi Predict / Compounds / SCHEMBL12606387

SCHEMBL12606387

SCHEMBL12606387

COCC1O[C@@H](O[C@H]2C(OC)C(OC)[C@@H](O[C@H]3C(OC)C(OC)[C@H](O[C@@H]4C(COS(=O)(=O)O)O[C@@H](O)C(OC)[C@H]4OC)O[C@H]3COC)O[C@H]2COC)C(OC)[C@@H](OC)[C@@H]1O[C@H]1OC(CN)[C@@H](O[C@@H]2O[C@@H](COS(=O)(=O)O)[C@@H](O[C@H]3O[C@@H](COS(=O)(=O)O)[C@@H](OSOOO)C(OSOOO)C3OSOOO)C(OSOOO)C2OS(=O)(=O)O)[C@H](OC)C1OC

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SERPINC1 P01008 3/20 0.43
▸ FGF1 P05230 4/20 0.38
▸ FGF2 P09038 1/20 0.38
▸ F10 P00742 5/20 0.36
▸ HPSE Q9Y251 5/20 0.33
▸ F2 P00734 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13039077 0.90 SERPINC1 (0.52) SERPINC1FGF1FGF2F10HPSE
SCHEMBL14363878 0.90 SERPINC1 (0.52) SERPINC1FGF1FGF2F10HPSE
SCHEMBL13039108 0.87 SERPINC1 (0.54) SERPINC1FGF1FGF2F10HPSE
SCHEMBL12606414 0.84 SERPINC1 (0.38) SERPINC1FGF1FGF2F10F2
SCHEMBL12920566 0.83 SERPINC1 (0.51) SERPINC1FGF1FGF2F10HPSE
SCHEMBL13039102 0.79 SERPINC1 (0.57) SERPINC1FGF1FGF2F10HPSE
SCHEMBL14363911 0.79 SERPINC1 (0.57) SERPINC1FGF1FGF2F10HPSE
SCHEMBL12920565 0.76 SERPINC1 (0.43) SERPINC1FGF1FGF2F10HPSE
SCHEMBL12606400 0.76 FGF1 (0.40) FGF1FGF2HPSE
SCHEMBL12606406 0.74 FGF1 (0.43) FGF1FGF2HPSEF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943595-B2 Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative SANOFI-AVENTIS (FR) 2011-05-17 — — US disclosed
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