SCHEMBL12606407

COCC1O[C@@H](O[C@H]2C(OC)C(OC)[C@@H](O[C@H]3C(OC)C(OC)[C@H](O[C@@H]4C(COS(=O)(=O)O)O[C@@H](O)C(OC)[C@H]4OC)O[C@H]3COC)O[C@H]2COC)C(OC)[C@@H](OC)[C@@H]1O[C@H]1OC(CNC(=O)CCCCCCC(=O)CCCCCNC(=O)CCCCC2SCC3NC(=O)NC32)[C@@H](O[C@@H]2O[C@@H](COS(=O)(=O)O)[C@@H](O[C@H]3O[C@@H](COS(=O)(=O)O)[C@@H](OSOOO)C(OSOOO)C3OSOOO)C(OSOOO)C2OS(=O)(=O)O)[C@H](OC)C1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	FGF1	P05230	1/20	0.42

▸	FGF2	P09038	1/20	0.42

▸	VEGFA	P15692	1/20	0.42

▸	HPSE	Q9Y251	1/20	0.42

▸	MDK	P21741	4/20	0.40

▸	PLCD1	P51178	1/20	0.37

▸	TDP1	Q9NUW8	2/20	0.36

▸	CA12	O43570	1/20	0.36

▸	CA1	P00915	1/20	0.36

▸	CA2	P00918	1/20	0.36

▸	CA9	Q16790	1/20	0.36

▸	CAPN1	P07384	2/20	0.35

▸	ITGB1	P05556	1/20	0.35

▸	ITGA4	P13612	1/20	0.35

▸	CNR1	P21554	3/20	0.35

▸	F2	P00734	1/20	0.34

▸	PRSS1	P07477	1/20	0.34

▸	PRSS2	P07478	1/20	0.34

▸	PRSS3	P35030	1/20	0.34

▸	TPSAB1	Q15661	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12606406	0.98	FGF1 (0.43)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL12606400	0.96	FGF1 (0.40)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL12606413	0.81	MDK (0.49)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL12606419	0.81	MDK (0.49)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL14363910	0.80	MDK (0.49)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL13039112	0.80	MDK (0.49)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL14363913	0.80	MDK (0.49)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL13039111	0.80	MDK (0.49)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL12606415	0.77	MDK (0.46)	FGF1FGF2VEGFAHPSEMDK
SCHEMBL29435448	0.75	MDK (0.53)	FGF1FGF2VEGFAHPSEMDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7943595-B2	Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative	SANOFI-AVENTIS (FR)	2011-05-17	—	—	US	disclosed