SCHEMBL29435448

SCHEMBL29435448

CO[C@H]1O[C@H](COS(=O)(=O)O)[C@@H](O[C@@H]2O[C@@H](C(=O)O)[C@@H](O[C@H]3O[C@H](COS(=O)(=O)O)[C@@H](O[C@@H]4O[C@H](C(=O)O)[C@@H](O[C@H]5O[C@H](COS(=O)(=O)O)[C@@H](OC)[C@H](OC)[C@H]5NC(=O)CCCCCNC(=O)CCCC[C@@H]5SC[C@@H]6NC(=O)N[C@@H]65)[C@H](OC)[C@H]4OC)[C@H](OS(=O)(=O)O)[C@H]3OS(=O)(=O)O)[C@H](OC)[C@H]2OC)[C@H](OS(=O)(=O)O)[C@H]1OS(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MDK P21741 4/20 0.53
▸ SERPINC1 P01008 3/20 0.49
▸ FGF1 P05230 1/20 0.48
▸ FGF2 P09038 1/20 0.48
▸ VEGFA P15692 1/20 0.48
▸ HPSE Q9Y251 1/20 0.48
▸ CAPN1 P07384 2/20 0.44
▸ TDP1 Q9NUW8 2/20 0.42
▸ F10 P00742 1/20 0.40
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ PLCD1 P51178 1/20 0.39
▸ F2 P00734 2/20 0.39
▸ ITGB1 P05556 1/20 0.38
▸ ITGA4 P13612 1/20 0.38
▸ CNR1 P21554 2/20 0.38
▸ PRSS1 P07477 1/20 0.37
▸ PRSS2 P07478 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12606419 0.91 MDK (0.49) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL12606413 0.91 MDK (0.49) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL13039111 0.88 MDK (0.49) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL13039112 0.88 MDK (0.49) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL14363910 0.88 MDK (0.49) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL14363913 0.88 MDK (0.49) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL12606415 0.87 MDK (0.46) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL12458589 0.83 MDK (0.51) MDKSERPINC1FGF1FGF2VEGFA
SCHEMBL13551197 0.81 MDK (0.49) MDKSERPINC1CAPN1F2PRSS1
SCHEMBL12799305 0.81 MDK (0.49) MDKSERPINC1FGF1FGF2VEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066065-A1 PLATELET DERIVATIVES FOR TREATING COAGULOPATHY CELLPHIRE, INC. (US) 2024-02-29 — — US claimed
US-11524978-B2 Synthetic peptides, pharmaceutical compositions comprising the same, and uses thereof in treating thromboembolism-related diseases ACADEMIA SINICA (TW) 2022-12-13 — — US claimed
US-20220380478-A1 ANTI-CD154 ANTIBODIES AND USES THEREOF TONIX PHARMACEUTICALS HOLDING CORP. 2022-12-01 — — US claimed
US-20220279777-A1 FREEZE-DRIED PLATELET DERIVATIVE COMPOSITIONS FOR TREATING ANTICOAGULANT-INDUCED COAGULOPATHY CELLPHIRE INC. (US) 2022-09-08 — — US claimed
WO-2022178191-A1 FREEZE-DRIED PLATELET DERIVATIVE COMPOSITIONS FOR TREATING ANTICOAGULANT-INDUCED COAGULOPATHY CELLPHIRE, INC. (US) 2022-08-25 — — WO claimed
EP-4013432-A1 THROMBOSOMES AS AN ANTICOAGULANT REVERSAL AGENT Cellphire Inc. (US) 2022-06-22 — — EP claimed
EP-3993876-A1 ANTI-CD154 ANTIBODIES AND USES THEREOF Tonix Pharma Limited (IE) 2022-05-11 — — EP claimed
US-11318331-B2 Pulmonary hypertension treatment SONIVIE LTD. (IL) 2022-05-03 — — US claimed
CN-114423785-A anti-CD 154 antibodies and uses thereof 通尼克斯制药有限公司 2022-04-29 — — CN claimed
EP-4747379-A1 AGENTS FOR TREATING CANCER Toumpoulis, Ioannis (GR) 2026-05-27 — — EP disclosed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 — — EP disclosed
US-20260115271-A1 MULTIVALENT PNEUMOCOCCAL VACCINES AFFINIVAX, INC. (US) 2026-04-30 — — US disclosed
EP-4728275-A1 METHODS AND ASSAYS FOR IMMUNE PHENOTYPING Immune Functional Diagnostics, LLC (US) 2026-04-22 — — EP disclosed
US-12605341-B2 Dry powder composition for peroral administration VICORE PHARMA AB (SE) 2026-04-21 — — US disclosed
EP-3980400-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS Emory University (US) 2022-04-13 — — EP disclosed
CN-114269296-A Methods and devices for treating iliac cavity compression, occlusion, vein caliber reduction, and occlusion-induced syndromes and conditions DP控股(英国)有限公司 2022-04-01 — — CN disclosed
EP-3965700-A1 METHODS AND DEVICES FOR TREATING ILIOCAVAL COMPRESSION, OCCLUSION, REDUCTION OF VENOUS CALIBER, AND SYNDROMES AND DISEASE STATES RESULTING FROM OCCLUSION DP Holding (U.K) Ltd. (GB) 2022-03-16 — — EP disclosed
WO-2022049372-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2022-03-10 — — WO disclosed
WO-2022051606-A1 NITRIC OXIDE DONORS, COMPOSITIONS, AND METHODS OF USE KNOW BIO, LLC (US) 2022-03-10 — — WO disclosed
US-20220047586-A1 COMPOSITION AND METHODS FOR PREVENTING OR REDUCING THE INCIDENCE OF TRANSIENT ISCHEMIC ATTACKS MOREHOUSE SCHOOL OF MEDICINE 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605341-B2 Dry powder composition for peroral administration GYS1, GYS2, SI MDK 3103/4885SERPINC1 3764/4885FGF1 1419/4885
US-20260115271-A1 MULTIVALENT PNEUMOCOCCAL VACCINES SPPL2B, SPAG5, SPPL2A MDK 3080/4885SERPINC1 1072/4885FGF1 4130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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