Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650955 | 0.98 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL12608375 | 0.84 | DRD2 (0.45) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL19996854 | 0.83 | RXRB (0.60) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL3838996 | 0.81 | RXRB (0.62) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11208311 | 0.80 | CYP1A2 (0.49) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6802503 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL16526945 | 0.79 | MAPK8 (0.54) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL5527444 | 0.79 | RXRB (0.65) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL12608382 | 0.79 | HRH3 (0.51) | CYP2D6 | |
| SCHEMBL8847933 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | HRH4, HRH3, HRH2 | ALDH1A1 1526/4885HPGD 1107/4885SMN1; SMN2 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.