Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 13/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12133749 | 0.98 | PDK2 (0.46) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12133751 | 0.98 | PDK2 (0.46) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12938317 | 0.98 | PDK2 (0.50) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL21394406 | 0.98 | PDK2 (0.50) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL21394230 | 0.98 | PDK2 (0.46) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL25068680 | 0.98 | PDK2 (0.50) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18878322 | 0.98 | PDK2 (0.50) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17151586 | 0.98 | PDK2 (0.50) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12133758 | 0.98 | PDK2 (0.46) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17151629 | 0.98 | PDK2 (0.50) | PDK2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951647-B2 | Organic electroluminescence device | MERCK PATENT GMBH (DE) | 2015-02-10 | — | — | US | disclosed |
| US-8951647-B2 | Organic electroluminescence device | MERCK PATENT GMBH (DE) | 2015-02-10 | — | — | US | disclosed |
| US-20110121274-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110121274-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110121274-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | ILK, PIEZO1, EPCAM | PDK2 246/4885MEN1 2232/4885KMT2A 3644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.