Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
| ▸ | ATF1 | P18846 | 3/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27838101 | 0.84 | XPO1 (0.40) | KDM4EASPHKDM8GFERNFKB1 | |
| SCHEMBL124693 | 0.84 | KDM4E (0.54) | KDM4ENPSR1NFKB1JUNNFKB2 | |
| SCHEMBL124714 | 0.80 | GFER (0.41) | KDM4EASPHGFERNPSR1NFKB1 | |
| SCHEMBL126304 | 0.76 | GFER (0.40) | KDM4EASPHGFERNFKB1JUN | |
| SCHEMBL121946 | 0.74 | XPO1 (0.42) | KDM4EASPHKDM8GFERNFKB1 | |
| SCHEMBL126280 | 0.73 | GFER (0.43) | KDM4EASPHGFERNPSR1NOTUM | |
| SCHEMBL127157 | 0.72 | KDM4E (0.52) | KDM4ENPSR1NFKB1JUNNFKB2 | |
| SCHEMBL127169 | 0.70 | ATF1 (0.43) | ASPHGFERNFKB1JUNNFKB2 | |
| SCHEMBL28007966 | 0.70 | ASPH (0.39) | KDM4EASPHGFERNFKB1JUN | |
| SCHEMBL126379 | 0.70 | GFER (0.38) | KDM4EASPHKDM8GFERNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102006777-B | Herbicidal compounds | SYNGENTA LTD | 2015-04-01 | — | — | CN | disclosed |
| US-8461083-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-06-11 | — | — | US | disclosed |
| EP-2265120-B1 | HERBICIDAL COUMPOUNDS | SYNGENTA LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| CN-102006777-A | Herbicidal coumpounds | SYNGENTA LTD | 2011-04-06 | — | — | CN | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2265120-A1 | HERBICIDAL COUMPOUNDS | Syngenta Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115788-A1 | HERBICIDAL COUMPOUNDS | SYNGENTA LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | KDM4E 1231/4885ASPH 1434/4885KDM8 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.