Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF1 | P18846 | 10/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 10/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 4/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121946 | 0.84 | XPO1 (0.42) | ATF1NFKB1XPO1ASPHJUN | |
| SCHEMBL28007966 | 0.82 | ASPH (0.39) | ATF1NFKB1XPO1ASPHJUN | |
| SCHEMBL28007979 | 0.82 | ASPH (0.39) | ATF1NFKB1HTTHSD17B10XPO1 | |
| SCHEMBL126304 | 0.82 | GFER (0.40) | ATF1NFKB1XPO1ASPHJUN | |
| SCHEMBL23119566 | 0.81 | ASPH (0.45) | ATF1NFKB1XPO1ASPHJUN | |
| SCHEMBL124767 | 0.80 | KDM4E (0.55) | ATF1NFKB1JUNNFKB2RELA | |
| SCHEMBL124761 | 0.79 | ATF1 (0.43) | ATF1NFKB1XPO1ASPHJUN | |
| SCHEMBL28007992 | 0.79 | ASPH (0.36) | ATF1NFKB1XPO1ASPHJUN | |
| SCHEMBL126978 | 0.79 | HPD (0.39) | ATF1NFKB1HTTHSD17B10XPO1 | |
| SCHEMBL28007962 | 0.77 | MAP4K4 (0.42) | GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102006777-B | Herbicidal compounds | SYNGENTA LTD | 2015-04-01 | — | — | CN | disclosed |
| US-8461083-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-06-11 | — | — | US | disclosed |
| EP-2265120-B1 | HERBICIDAL COUMPOUNDS | SYNGENTA LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| CN-102006777-A | Herbicidal coumpounds | SYNGENTA LTD | 2011-04-06 | — | — | CN | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2265120-A1 | HERBICIDAL COUMPOUNDS | Syngenta Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115788-A1 | HERBICIDAL COUMPOUNDS | SYNGENTA LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | ATF1 3837/4885NFKB1 2092/4885HTT 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.