SCHEMBL126187

SCHEMBL126187

O=C(O)c1c(I)cc(I)c(O)c1I

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.47
TSHR P16473 1/20 0.47
TPMT P51580 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
TTR P02766 2/20 0.39
LMNA P02545 3/20 0.38
PARG Q86W56 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
THRB P10828 2/20 0.38
ALOX12 P18054 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
GLRA3 O75311 1/20 0.38
GLRB P48167 1/20 0.38
TP53 P04637 2/20 0.37
DPP4 P27487 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386792 1.00 MAPK1 (0.47) MAPK1TSHRTPMTTDP1TTR
SCHEMBL377395 0.85 MAPK1 (0.53) MAPK1TSHRTPMTTDP1LMNA
Hydrochloric Acid SCHEMBL11407766 0.83 MAPK1 (0.52) MAPK1TSHRTPMTTDP1ALDH1A1
SCHEMBL23600928 0.82 TPMT (0.48) MAPK1TSHRTPMTTDP1TTR
SCHEMBL21783790 0.82 TPMT (0.48) MAPK1TSHRTPMTTDP1TTR
SCHEMBL4277000 0.81 TPMT (0.52) MAPK1TSHRTPMTTDP1ALDH1A1
SCHEMBL31409214 0.81 TPMT (0.52) MAPK1TSHRTPMTTDP1ALDH1A1
SCHEMBL31518592 0.80 TSHR (0.39) MAPK1TSHRTPMTTDP1TTR
SCHEMBL22991367 0.80 TTR (0.42) MAPK1TSHRTDP1TTRLMNA
SCHEMBL10495744 0.80 TSHR (0.39) MAPK1TSHRTPMTTDP1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114008013-B Treatment of CNS disorders with sleep disorders 哥本哈根大学 2026-05-15 CN claimed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 US claimed
CN-118731332-A Kidney-power triple detection test card and corresponding calibration method and system 江苏康尚医学科技有限公司 2024-10-01 CN claimed
CN-115896236-A Detection kit and detection method for alanine aminotransferase 北京安图生物工程有限公司 2023-04-04 CN claimed
CN-114480565-A Stable high-sensitivity glycated albumin determination kit with strong anti-interference capability 桂林优利特医疗电子有限公司 2022-05-13 CN claimed
CN-114134201-A Production process of 1, 5-dehydration-D-sorbitol detection reagent by adopting enzyme method 苏州普瑞斯生物科技有限公司 2022-03-04 CN claimed
CN-114057600-A X-ray developable molecule, drug-loaded embolism microsphere and preparation method thereof 上海汇禾医疗科技有限公司 2022-02-18 CN claimed
US-20210069352-A1 IODINE-BASED PARTICLES NANOPROBES, INC. 2021-03-11 US claimed
CN-109212238-B Glycated albumin assay kit 山东博科生物产业有限公司 2020-04-28 CN claimed
CN-110846378-A 1, 5-sorbitan detection kit and preparation method thereof 苏州普瑞斯生物科技有限公司 2020-02-28 CN claimed
US-6537823-B1 Use in determination of adulterants in illicit drug screening samples as a means of detecting false negative results SCITECK DIAGNOSTICS, INC. 2003-03-25 US claimed
US-20030045003-A1 Method for detection of the adulterant urine luckTM in urine using liquid chemistry, dry chemistry test pads, and lateral flow SMITH JACK V (US) 2003-03-06 US claimed
US-20030027350-A1 Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads, and lateral flow SMITH JACK V (US) 2003-02-06 US claimed
EP-0378395-B1 Method of measuring cholesterol, diagnosing vascular disease, and raising HDL cholesterol levels MAINES ROBERT Q (US) 1996-08-14 EP claimed
US-5094943-A Superoxide dimutase BOEHRINGER MANNHEIM GMBH (DE) 1992-03-10 US claimed
EP-0378395-A2 Method of measuring cholesterol, diagnosing vascular disease, and raising HDL cholesterol levels Maines, Robert Q. (US) 1990-07-18 EP claimed
EP-0186134-B1 MEANS FOR IMPROVING THE DETERMINATION OF OXIDASE REACTIONS PRODUCING HYDROGEN PEROXYDE, AND THEIR USE Roche Diagnostics GmbH (DE) 1989-02-15 EP claimed
EP-0101799-B1 HIGH GLUCOSE-DETERMINING ANALYTICAL ELEMENT MILES LABORATORIES, INC. (US) 1985-12-04 EP claimed
EP-0101799-A1 High glucose-determining analytical element MILES LABORATORIES, INC. (US) 1984-03-07 EP claimed
US-4427770-A BLOOD GLUCOSE MILES LABORATORIES, INC. (US) 1984-01-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 MAPK1 2951/4885TSHR 1900/4885TPMT 4383/4885
US-20210069352-A1 IODINE-BASED PARTICLES TPO, BRI3BP, INSRR MAPK1 3330/4885TSHR 25/4885TPMT 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.