SCHEMBL12620162

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12599964	0.83	KDM4E (0.38)	KDM4EGAAGLAPARP10PARP11
	SCHEMBL31417561	0.79	SOS1 (0.47)	KDM4EATMCA1CA2CA9
	SCHEMBL38658847	0.77	CA1 (0.42)	KDM4EGAAGLAATMCA1
	SCHEMBL29323701	0.77	KDM4E (0.36)	KDM4EGAAGLAATMCA1
	SCHEMBL18397725	0.74	SLC6A3 (0.40)	KDM4EGAAGLAATMCA1
	SCHEMBL5328082	0.74	PARP1 (0.53)	KDM4EGAAGLAPARP1ABL1
	SCHEMBL31488066	0.73	RXFP1 (0.46)	PARP10PARP11CA1CA2CA9
	SCHEMBL21955273	0.72	KDM4E (0.35)	KDM4EGAAGLAATMCA1
	SCHEMBL13181933	0.72	KDM4E (0.47)	KDM4EGAAGLAPARP10PARP11
	SCHEMBL10661545	0.72	KDM4E (0.45)	KDM4EATMPOLBPARP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.