Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21955273 | 0.90 | KDM4E (0.35) | KDM4EALDH1A1LMNAHSD17B10RET | |
| SCHEMBL4486453 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| SCHEMBL18789711 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1LMNAHSD17B10RET | |
| SCHEMBL12620162 | 0.77 | KDM4E (0.37) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| SCHEMBL29323699 | 0.76 | KDM4E (0.38) | KDM4EGLAGAAALOX5NR4A2 | |
| SCHEMBL13603023 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| SCHEMBL31056598 | 0.76 | SLC6A2 (0.37) | ALOX5KMT2ACSNK2A1SLC6A2SLC6A4 | |
| SCHEMBL29323708 | 0.76 | SLC6A2 (0.37) | ALOX5KMT2ACSNK2A1SLC6A2SLC6A4 | |
| SCHEMBL29323704 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1LMNAHSD17B10RET | |
| SCHEMBL30517094 | 0.75 | ALOX5 (0.51) | KDM4EALDH1A1LMNAHSD17B10ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |