Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.58 |
| ▸ | RELA | Q04206 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049347 | 0.89 | RAB9A (0.71) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL1046569 | 0.89 | RAB9A (0.71) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL11976542 | 0.89 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9081648 | 0.87 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL12622324 | 0.87 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL11976567 | 0.85 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL11976425 | 0.85 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL11976559 | 0.84 | RAB9A (0.61) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9082721 | 0.84 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL10556991 | 0.83 | RAB9A (0.82) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110108770-A1 | COMPOSITION COMPRISING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
| US-20110108770-A1 | COMPOSITION COMPRISING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
| EP-2287940-A1 | COMPOSITION CONTAINING NITROGENOUS HETEROCYCLIC COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2011-02-23 | — | — | EP | disclosed |