Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 10/20 | 0.76 |
| ▸ | F13A1 | P00488 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TGM1 | P22735 | 1/20 | 0.51 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ITK | Q08881 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81209 | 0.87 | TGM2 (1.00) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL1262280 | 0.87 | TGM2 (0.71) | TGM2F13A1LMNATGM1TGM3 | |
| Dimethylamine SCHEMBL1263117 | 0.85 | TGM2 (0.88) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL28240522 | 0.85 | TGM2 (0.96) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL30211836 | 0.85 | TGM2 (0.96) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL1262770 | 0.84 | TGM2 (0.67) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL21247525 | 0.82 | TGM2 (0.81) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL1700934 | 0.82 | TGM2 (0.88) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL19501652 | 0.80 | TGM2 (0.85) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL261812 | 0.80 | TGM2 (0.85) | TGM2F13A1LMNATGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7881648-B2 | Positive charge control resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus | CANON KASEI KABUSHIKI KAISHA (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20080247787-A1 | Positive Charge Control Resin for Electrophotographic Functional Component Parts, Developing Roller, and Electrophotographic Apparatus | CANON KASEI KABUSHIKI KAISHA (JP) | 2008-10-09 | — | — | US | disclosed |
| WO-2006134788-A1 | POSITIVE CHARGE CONTROL RESIN FOR ELECTROPHOTOGRAPHIC FUNCTIONAL COMPONENT PARTS, DEVELOPING ROLLER, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KASEI KABUSHIKI KAISHA (JP) | 2006-12-21 | — | — | WO | disclosed |