SCHEMBL261812

SCHEMBL261812

C=CC(=O)Nc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 10/20 0.85
CASP3 P42574 1/20 0.62
SENP7 Q9BQF6 1/20 0.62
F13A1 P00488 1/20 0.61
LMNA P02545 1/20 0.61
TGM1 P22735 1/20 0.61
TGM3 Q08188 1/20 0.61
EGFR P00533 1/20 0.59
ITK Q08881 1/20 0.59
MAPT P10636 6/20 0.58
GAA P10253 2/20 0.58
GFER P55789 1/20 0.58
POLB P06746 1/20 0.58
FYN P06241 1/20 0.56
SRC P12931 1/20 0.56
MEN1 O00255 3/20 0.53
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 3/20 0.53
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81209 0.92 TGM2 (1.00) TGM2F13A1LMNATGM1TGM3
SCHEMBL30211836 0.90 TGM2 (0.96) TGM2F13A1LMNATGM1TGM3
SCHEMBL28240522 0.90 TGM2 (0.96) TGM2F13A1LMNATGM1TGM3
SCHEMBL19501652 0.89 TGM2 (0.85) TGM2CASP3SENP7F13A1LMNA
Dimethylamine SCHEMBL1263117 0.86 TGM2 (0.88) TGM2F13A1LMNATGM1TGM3
SCHEMBL1700934 0.86 TGM2 (0.88) TGM2F13A1LMNATGM1TGM3
SCHEMBL439369 0.85 TGM2 (0.79) TGM2F13A1LMNATGM1TGM3
SCHEMBL1383664 0.85 TGM2 (0.78) TGM2F13A1LMNATGM1TGM3
Sulfuric Acid SCHEMBL10783007 0.85 TGM2 (0.85) TGM2F13A1LMNATGM1TGM3
SCHEMBL11502177 0.84 CASP3 (0.67) TGM2CASP3SENP7EGFRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 944 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025102500-A1 NITRILE RUBBER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油天然气股份有限公司 2025-05-22 WO claimed
CN-119978235-A Nitrile rubber and preparation method and application thereof 中国石油天然气股份有限公司 2025-05-13 CN claimed
US-10858455-B2 Process for the production of water and solvent-free nitrile rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2020-12-08 US claimed
US-20160369014-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2016-12-22 US claimed
EP-2478021-B1 Nitrile rubbers and production of same in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-11-04 EP claimed
CN-102498140-B Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH 2015-06-24 CN claimed
CN-103450397-B Preparation method of nitrile rubber PETROCHINA CO LTD 2015-05-13 CN claimed
US-9023914-B2 Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-05-05 US claimed
EP-2641909-A1 Transition metal P-N complexes as polymerization catalysts LANXESS Deutschland GmbH (DE) 2013-09-25 EP claimed
US-20120283351-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2012-11-08 US claimed
CN-102498140-A Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH 2012-06-13 CN claimed
US-5936038-A MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE THE UNIVERSITY OF AKRON (US) 1999-08-10 US claimed
US-4386181-A CONJUGATED DIENE, N-/ANILINOPHENYL/ACRYLAMIDE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-05-31 US claimed
US-4376846-A OIL AND OZONE RESISTANT AND HEAT AGING RESISTANT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-03-15 US claimed
US-4354007-A Process for preparing oxidatively-stable polymers SCOTT GERALD 1982-10-12 US claimed
US-4300615-A Fabric composite and rubber reinforced therewith THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 US claimed
JP-54157148-A None JP disclosed
US-12626944-B2 Antioxidant substituted sulfonated ion exchange membranes THE LUBRIZOL CORPORATION (US) 2026-05-12 US disclosed
US-3928296-A Stabilization of vinylidene chloride/diene copolymers GOODYEAR TIRE & RUBBER 1975-12-23 US disclosed
US-3867334-A Antihardeners for polymers GOODYEAR TIRE & RUBBER 1975-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12626944-B2 Antioxidant substituted sulfonated ion exchange membranes MPC2, GPX4, PCCA TGM2 2215/4885CASP3 457/4885SENP7 3529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.