Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12626734 | 0.98 | KISS1R (0.90) | KISS1R | |
| SCHEMBL12624944 | 0.98 | KISS1R (0.90) | KISS1R | |
| SCHEMBL13874924 | 0.98 | KISS1R (0.90) | KISS1R | |
| SCHEMBL29560920 | 0.98 | KISS1R (0.90) | KISS1R | |
| SCHEMBL12624708 | 0.98 | KISS1R (0.90) | KISS1R | |
| SCHEMBL13892031 | 0.98 | KISS1R (0.90) | KISS1R | |
| SCHEMBL12624943 | 0.96 | KISS1R (0.87) | KISS1R | |
| SCHEMBL12625590 | 0.96 | KISS1R (0.87) | KISS1R | |
| SCHEMBL13892025 | 0.96 | KISS1R (0.86) | KISS1R | |
| SCHEMBL12625846 | 0.96 | KISS1R (0.86) | KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404643-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-7960348-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20100331520-A1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20090105152-A1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| US-20090099334-A1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-16 | — | — | US | disclosed |
| US-20090099334-A1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-16 | — | — | US | disclosed |
| US-20090093615-A1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099334-A1 | METASTIN DERIVATIVES AND USE THEREOF | SHBG, GNRHR, INHA | KISS1R 96/4885 |
| US-20100331520-A1 | METASTIN DERIVATIVES AND USE THEREOF | SHBG, GNRHR, INHA | KISS1R 96/4885 |
| US-20090093615-A1 | METASTIN DERIVATIVES AND USE THEREOF | SHBG, GNRHR, INHA | KISS1R 96/4885 |
| US-20090105152-A1 | METASTIN DERIVATIVES AND USE THEREOF | SHBG, GNRHR, INHA | KISS1R 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.