Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.64 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 2/20 | 0.42 |
| ▸ | GRM6 | O15303 | 2/20 | 0.42 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.42 |
| ▸ | GGH | Q92820 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201753 | 0.79 | FOLH1 (1.00) | FOLH1GRM3NAALAD2GRM8GRM6 | |
| Phosphonic Acid SCHEMBL15193462 | 0.72 | FOLH1 (0.84) | FOLH1GRM3NAALAD2GRM8GRM6 | |
| SCHEMBL9181835 | 0.68 | FOLH1 (0.59) | FOLH1GRM3NAALAD2GRM8GRM6 | |
| SCHEMBL10336815 | 0.67 | FOLH1 (0.57) | FOLH1GRM3NAALAD2GRM8GRM6 | |
| SCHEMBL9461890 | 0.67 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 | |
| SCHEMBL11293793 | 0.67 | FOLH1 (0.68) | FOLH1GRM3NAALAD2 | |
| SCHEMBL11396532 | 0.65 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8633245 | 0.64 | FOLH1 (0.60) | FOLH1GRM3NAALAD2GRM8GRM6 | |
| SCHEMBL1850194 | 0.64 | FOLH1 (0.60) | FOLH1GRM3NAALAD2GGHTET2 | |
| D-Glutamate SCHEMBL1065173 | 0.64 | GRM8 (0.82) | FOLH1GRM3GRM8GRM6GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073286-A1 | PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-23 | — | — | WO | disclosed |