SCHEMBL1850194

SCHEMBL1850194

O=C(O)CCC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.60
NAALAD2 Q9Y3Q0 1/20 0.56
FDPS P14324 3/20 0.50
GRM3 Q14832 2/20 0.50
CYP1A2 P05177 1/20 0.48
GGH Q92820 1/20 0.45
TET2 Q6N021 3/20 0.44
KDM4A O75164 2/20 0.44
KDM4C Q9H3R0 2/20 0.44
KDM2A Q9Y2K7 2/20 0.44
TET3 O43151 1/20 0.44
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1169260 0.87 FOLH1 (0.48) FOLH1NAALAD2FDPSGRM3CYP1A2
SCHEMBL21611867 0.85 FOLH1 (0.59) FOLH1NAALAD2FDPSLMNATSHR
SCHEMBL5011486 0.83 FDPS (0.56) FOLH1NAALAD2FDPSLMNATSHR
SCHEMBL328880 0.81 FDPS (0.57) FOLH1FDPSLMNATSHR
SCHEMBL8633245 0.79 FOLH1 (0.60) FOLH1NAALAD2GRM3CYP1A2GGH
SCHEMBL6037144 0.77 FOLH1 (0.58) FOLH1NAALAD2GRM3CYP1A2GGH
SCHEMBL9176133 0.77 FDPS (0.54) FOLH1FDPSLMNA
SCHEMBL10785210 0.76 FDPS (0.67) FDPS
SCHEMBL1191457 0.75 FOLH1 (0.56) FOLH1NAALAD2GRM3CYP1A2
SCHEMBL2201753 0.75 FOLH1 (1.00) FOLH1NAALAD2GRM3CYP1A2GGH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9694357-B1 Multi-acid polymers and methods of making the same NISSAN NORTH AMERICA, INC. (US) 2017-07-04 US claimed
US-20240390504-A1 MULTIFUNCTIONAL CONJUGATES E P O S IASIS RES AND DEVELOPMENT LIMITED (CY) 2024-11-28 US disclosed
US-11969473-B2 Multifunctional conjugates E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) 2024-04-30 US disclosed
US-20230027148-A1 MULTIFUNCTIONAL CONJUGATES E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) 2023-01-26 US disclosed
US-11400160-B2 Multifunctional conjugates E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) 2022-08-02 US disclosed
US-10930961-B2 Multi-acid polymers from multifunctional amino phosphonic acids and sulfonyl halide precursors and methods of making the same NISSAN NORTH AMERICA, INC. (US) 2021-02-23 US disclosed
US-20200164076-A1 MULTIFUNCTIONAL CONJUGATES E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) 2020-05-28 US disclosed
EP-3648797-A1 MULTIFUNCTIONAL CONJUGATES EPOS-Iasis Research and Development, Ltd (CY) 2020-05-13 EP disclosed
US-10468701-B2 Multi-acid polymers from multifunctional amino acids and sulfonyl halide precursors and methods of making the same NISSAN NORTH AMERICA, INC. (US) 2019-11-05 US disclosed
US-20190013538-A1 Multi-Acid Polymers From Multifunctional Amino Acids and Sulfonyl Halide Precursors and Methods of Making the Same NISSAN MOTOR CO., LTD. (JP) 2019-01-10 US disclosed
WO-2008125422-A2 USE OF METAL NANOPARTICLES FOR DIAGNOSING ALZHEIMER DISEASE GUERBET (FR) 2008-10-23 WO disclosed
WO-2007138381-A2 PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS TARGANTA THERAPEUTICS INC. (CA) 2007-12-06 WO disclosed
US-20060239913-A1 Peptide conjugate for magnetic resonance imaging GUERBET (FR) 2006-10-26 US disclosed
EP-1635878-A2 PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING GUERBET (FR) 2006-03-22 EP disclosed
WO-2004112840-A2 PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING GUERBET (FR) 2004-12-29 WO disclosed
US-20040253181-A1 Novel compositions magnetic particles covered with gem-bisphosphonate derivatives GUERBET (FR) 2004-12-16 US disclosed
US-6140518-A Steroid bisphosphonates THE UNIVERSITY OF LIVERPOOL (GB) 2000-10-31 US disclosed
EP-0036162-A1 Low-phosphate foam regulated detergent Henkel Kommanditgesellschaft auf Aktien (DE) 1981-09-23 EP disclosed
US-4120890-A ANTIPLAQUE, ANTITARTAR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-10-17 US disclosed
US-4077997-A SEQUESTERING AGENTS, BASIC CATALYST, SAPONIFICATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DT) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11969473-B2 Multifunctional conjugates MKI67, ACP3, CD44 FOLH1 225/4885NAALAD2 915/4885FDPS 489/4885
US-20230027148-A1 MULTIFUNCTIONAL CONJUGATES MKI67, ACP3, CD44 FOLH1 225/4885NAALAD2 915/4885FDPS 489/4885
US-20200164076-A1 MULTIFUNCTIONAL CONJUGATES MKI67, ACP3, CD44 FOLH1 215/4885NAALAD2 895/4885FDPS 467/4885
US-20060239913-A1 Peptide conjugate for magnetic resonance imaging MMP11, MMP26, MMP3 FOLH1 87/4885NAALAD2 86/4885FDPS 4083/4885
US-20240390504-A1 MULTIFUNCTIONAL CONJUGATES MKI67, ACP3, CD44 FOLH1 225/4885NAALAD2 915/4885FDPS 489/4885
US-11400160-B2 Multifunctional conjugates MKI67, ACP3, CD44 FOLH1 215/4885NAALAD2 895/4885FDPS 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.