SCHEMBL1263017

SCHEMBL1263017

C=C(C)C(=O)OCCC(CP(=O)(O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 10/20 0.49
NAALAD2 Q9Y3Q0 1/20 0.49
THRB P10828 1/20 0.41
TSHR P16473 3/20 0.40
GRM3 Q14832 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446719 0.88 TSHR (0.50) FOLH1NAALAD2THRBTSHRGRM3
SCHEMBL1263342 0.88 TSHR (0.50) FOLH1NAALAD2THRBTSHRGRM3
SCHEMBL1263800 0.88 TSHR (0.50) FOLH1NAALAD2THRBTSHRGRM3
SCHEMBL3448822 0.88 TSHR (0.50) FOLH1NAALAD2THRBTSHRGRM3
SCHEMBL1436427 0.88 TSHR (0.50) FOLH1NAALAD2THRBTSHRGRM3
SCHEMBL18492409 0.85 THRB (0.50) FOLH1THRBTSHR
SCHEMBL15396854 0.84 FOLH1 (0.47) FOLH1NAALAD2THRBTSHR
Ammonia Solution, Strong SCHEMBL18492401 0.83 THRB (0.48) FOLH1THRBTSHR
SCHEMBL1264172 0.82 FOLH1 (0.47) FOLH1NAALAD2THRBTSHR
SCHEMBL30790578 0.80 THRB (0.50) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583197-B1 Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent KABUSHIKI KAISHA SHOFU (JP) 2003-06-24 US claimed
US-7879924-B2 Dental composite resin cement, dental primer and dental adhesive kit containing them KABUSHIKI KAISHA SHOFU (JP) 2011-02-01 US disclosed
US-20090048366-A1 Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them KABUSHIKI KAISHA SHOFU (JP) 2009-02-19 US disclosed
EP-1066813-B1 Dental adhesive composition SHOFU KK (JP) 2004-10-06 EP disclosed
US-6583197-B1 Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent KABUSHIKI KAISHA SHOFU (JP) 2003-06-24 US disclosed
EP-1066813-A2 Dental adhesive composition KABUSHIKI KAISHA SHOFU (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048366-A1 Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them CDH1, JMJD7, WDR91 FOLH1 1259/4885NAALAD2 2013/4885THRB 2753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.