Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 14/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12630227 | 0.83 | DUT (0.67) | DUTACACB | |
| SCHEMBL12629740 | 0.79 | DUT (0.75) | DUT | |
| SCHEMBL12630219 | 0.79 | DUT (0.66) | DUT | |
| SCHEMBL22751583 | 0.79 | DUT (0.56) | DUTCNR2ACACB | |
| SCHEMBL21315518 | 0.75 | DUT (0.66) | DUT | |
| SCHEMBL21315519 | 0.75 | DUT (0.66) | DUT | |
| SCHEMBL21315516 | 0.75 | DUT (0.66) | DUT | |
| SCHEMBL12630551 | 0.75 | DUT (0.66) | DUT | |
| SCHEMBL12630553 | 0.74 | DUT (0.67) | DUT | |
| SCHEMBL21690773 | 0.74 | DUT (0.64) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011065545-A1 | 5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2011-06-03 | — | — | WO | disclosed |