SCHEMBL12630219 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	DUT	P33316	7/20	0.66

▸	LOXL2	Q9Y4K0	3/20	0.41

▸	AOC3	Q16853	2/20	0.41

▸	ADAMTS4	O75173	4/20	0.41

▸	CA2	P00918	1/20	0.41

▸	ALDH1A1	P00352	1/20	0.39

▸	MEN1	O00255	2/20	0.39

▸	KMT2A	Q03164	2/20	0.39

▸	POLB	P06746	1/20	0.39

▸	HCRTR1	O43613	1/20	0.39

▸	LMNA	P02545	1/20	0.39

▸	MAPT	P10636	1/20	0.39

▸	TSHR	P16473	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12630227	0.83	DUT (0.67)	DUT
SCHEMBL12630213	0.79	DUT (0.67)	DUT
SCHEMBL12630248	0.79	DUT (0.76)	DUTLMNA
SCHEMBL12630552	0.74	DUT (0.64)	DUT
SCHEMBL12630519	0.74	DUT (0.66)	DUTALDH1A1MEN1KMT2APOLB
SCHEMBL15247629	0.73	DUT (0.48)	DUTTSHR
SCHEMBL21690775	0.72	DUT (0.62)	DUT
SCHEMBL12630555	0.72	DUT (0.62)	DUT
SCHEMBL21691000	0.72	DUT (0.69)	DUT
SCHEMBL12630554	0.71	DUT (0.67)	DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011065545-A1	5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF	大鵬薬品工業株式会社 (JP)	2011-06-03	—	—	WO	disclosed