SCHEMBL1263085

SCHEMBL1263085

CO/C=C(/C(=O)OC)c1ccccc1CBr

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 3/20 0.39
KDM4E B2RXH2 2/20 0.36
RCE1 Q9Y256 1/20 0.36
ATM Q13315 1/20 0.35
TSHR P16473 1/20 0.35
HIF1A Q16665 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5257837 1.00 ALDH1A1 (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL29437612 1.00 ALDH1A1 (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL5257839 1.00 ALDH1A1 (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL6156562 0.88 ALDH1A1 (0.43) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL8035923 0.88 ALDH1A1 (0.43) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL5669568 0.88 ALDH1A1 (0.43) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL9944266 0.88 HPGD (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL10613848 0.87 MEN1 (0.44) ALDH1A1LMNATSHRSMN1; SMN2TDP1
SCHEMBL10613841 0.87 MEN1 (0.44) ALDH1A1LMNATSHRSMN1; SMN2TDP1
SCHEMBL7223627 0.87 ALDH1A1 (0.38) ALDH1A1LMNAHPGDKDM4ERCE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114763330-A Trifluoroethyl sulfide (sulfoxide) substituted benzene compound and application thereof 沈阳化工大学 2022-07-19 CN disclosed
CN-108530335-B Indole compound and preparation method and application thereof 华南农业大学 2021-08-31 CN disclosed
WO-2017125010-A1 NOVEL CRYSTALLINE FORM OF PICOXYSTROBIN, METHOD OF PREPARING AND USE OF THE SAME JIANGSU ROTAM CHEMISTRY CO., LTD. (CN) 2017-07-27 WO disclosed
US-9422254-B2 Methoxyacrylate-based fungicide and methods for preparing and using the same Central China Normal University (CN) 2016-08-23 US disclosed
US-9422254-B2 Methoxyacrylate-based fungicide and methods for preparing and using the same Central China Normal University (CN) 2016-08-23 US disclosed
US-8772290-B2 Alpha-arylmethoxyacrylate derivative, preparation method thereof, and pharmaceutical composition containing same Oscotech Inc. (KR) 2014-07-08 US disclosed
EP-2565180-A2 ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Oscotec Inc. (KR) 2013-03-06 EP disclosed
US-8383640-B2 Substituted pyrimidine ether compounds and use thereof SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2013-02-26 US disclosed
US-8383640-B2 Substituted pyrimidine ether compounds and use thereof SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2013-02-26 US disclosed
US-8227456-B2 Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyacrylate derivatives KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2012-07-24 US disclosed
WO-1994005620-A1 CHEMICAL PROCESS ZENECA LIMITED (GB) 1994-03-17 WO disclosed
EP-0586393-A1 SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES ZENECA LIMITED (GB) 1994-03-16 EP disclosed
WO-1993008180-A1 BENZOXAZOLE, BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES AS FUNGICIDES ZENECA LIMITED (GB) 1993-04-29 WO disclosed
US-5194622-A Chemical condensation of an aldehyde of an azole and a phosphonium derivative ROUSSEL UCLAF (FR) 1993-03-16 US disclosed
WO-1992018487-A1 SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES ZENECA LIMITED (GB) 1992-10-29 WO disclosed
EP-0506149-A2 Fungicides ZENECA LIMITED (GB) 1992-09-30 EP disclosed
US-5055471-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-08 US disclosed
US-5021581-A Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-04 US disclosed
EP-0370629-A1 Fungicides ZENECA LIMITED (GB) 1990-05-30 EP disclosed
EP-0278595-A2 Fungicides ZENECA LIMITED (GB) 1988-08-17 EP disclosed