SCHEMBL8035923

SCHEMBL8035923

C/C=C(\C(=O)OC)c1ccccc1CBr

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
HPGD P15428 4/20 0.41
KDM4E B2RXH2 2/20 0.38
RCE1 Q9Y256 1/20 0.38
TSHR P16473 2/20 0.37
ATM Q13315 1/20 0.37
HIF1A Q16665 1/20 0.37
HTT P42858 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KCNA5 P22460 1/20 0.36
CTSD P07339 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156562 1.00 ALDH1A1 (0.43) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL5669568 1.00 ALDH1A1 (0.43) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL5998396 0.89 ALDH1A1 (0.42) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL5998392 0.89 ALDH1A1 (0.42) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL29437612 0.88 ALDH1A1 (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL1263085 0.88 ALDH1A1 (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL5257839 0.88 ALDH1A1 (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL5257837 0.88 ALDH1A1 (0.41) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL27519602 0.88 ALDH1A1 (0.44) ALDH1A1LMNAHPGDKDM4ERCE1
SCHEMBL9264654 0.86 ALDH1A1 (0.40) ALDH1A1LMNAHPGDKDM4ERCE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5213815-A None JP disclosed
US-6166026-A 2-(O-[pyrimidin-4-yl]methyleneoxy)phenylacetic acid derivatives and their use in combatting noxious fungi and animal pests BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
US-5998446-A INSECTICIDE; MITICIDE; NEMATOCIDE BASF AKTIENGESELLSCHAFT (DE) 1999-12-07 US disclosed
US-5416068-A Alpha-phenylacrylic acid derivatives, their preparation and their use for controlling pests and harmful fungi BASF AKTIENGESELLSCHAFT (DE) 1995-05-16 US disclosed
US-5298527-A Insecticides BASF AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
US-5254717-A Imino-substituted phenyl derivatives, the preparation thereof and fungicides containing these BASF AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
JP-H05213815-A ALPHA-PHENYLACRYLIC ACID DERIVATIVE AND METHOD FOR CONTROLLING HARMFUL INSECTS AND FUNGI USING THE SAME BASF AG 1993-08-24 JP disclosed