SCHEMBL1263164

SCHEMBL1263164

C=CC(=O)OCc1ccc(N(CCC)CCC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.44
ESRRG P62508 2/20 0.44
HPGD P15428 4/20 0.40
TSHR P16473 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CNR2 P34972 1/20 0.39
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPT P10636 2/20 0.37
HCAR2 Q8TDS4 1/20 0.36
RORC P51449 1/20 0.35
THRA P10827 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262293 0.92 THRB (0.46) THRBESRRGHPGDTSHRCNR2
SCHEMBL1262782 0.88 MAPT (0.44) THRBESRRGHPGDTSHRNPSR1
SCHEMBL9659189 0.86 THRB (0.49) THRBESRRGHPGDTSHRNPSR1
SCHEMBL10092988 0.84 THRB (0.44) THRBHPGDTSHRALDH1A1KDM4E
SCHEMBL960603 0.81 ALDH1A1 (0.55) THRBHPGDTSHRL3MBTL1ALDH1A1
SCHEMBL13777615 0.81 THRB (0.45) THRBESRRGHPGDTSHRTHRA
SCHEMBL2602454 0.81 THRB (0.42) THRBHPGDTSHRCNR2ALDH1A1
SCHEMBL11987082 0.81 THRB (0.42) THRBHPGDTSHRCNR2ALDH1A1
SCHEMBL2556244 0.80 HCAR2 (0.50) THRBHPGDTSHRL3MBTL1ALDH1A1
SCHEMBL1263110 0.80 THRB (0.59) THRBESRRGHPGDTSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7881648-B2 Positive charge control resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2011-02-01 US disclosed
US-20080247787-A1 Positive Charge Control Resin for Electrophotographic Functional Component Parts, Developing Roller, and Electrophotographic Apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
WO-2006134788-A1 POSITIVE CHARGE CONTROL RESIN FOR ELECTROPHOTOGRAPHIC FUNCTIONAL COMPONENT PARTS, DEVELOPING ROLLER, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KASEI KABUSHIKI KAISHA (JP) 2006-12-21 WO disclosed
US-6033819-A FIXABLE COMPONENT HAS A MICRO PHASE SEPARATION STRUCTURE OF A LIQUID CONTINUOUS PHASE AND A DISPERSE PHASE CONTAINING A RESIN AND HAVING A GLASS TRANSITION TEMPERATURE OF NOT HIGHER THAN 20 DEGREES, CONTAINING A BLOCK OR GRAFT POLYMER FUJI XEROX CO., LTD. (JP) 2000-03-07 US disclosed