Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 14/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9964421 | 0.90 | PDCD1 (0.43) | CD274PDCD1 | |
| SCHEMBL9964438 | 0.90 | CD274 (0.38) | CD274PDCD1FFAR1 | |
| SCHEMBL9964425 | 0.85 | CD274 (0.39) | CD274PDCD1FFAR1 | |
| SCHEMBL9964422 | 0.81 | PDCD1 (0.37) | CD274PDCD1 | |
| SCHEMBL9964429 | 0.81 | ESR1 (0.34) | CD274PDCD1FFAR1 | |
| SCHEMBL9964419 | 0.80 | CD274 (0.41) | CD274PDCD1FFAR1 | |
| SCHEMBL9964444 | 0.80 | CD274 (0.36) | CD274PDCD1FFAR1 | |
| SCHEMBL9964420 | 0.80 | DRD2 (0.35) | CD274PDCD1FFAR1 | |
| SCHEMBL9964414 | 0.80 | FFAR1 (0.38) | CD274PDCD1FFAR1 | |
| SCHEMBL9964424 | 0.79 | CD274 (0.33) | CD274PDCD1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078371-A1 | NOVEL 3-HYDROXY-5-ARYLISOTHIAZOLE DERIVATIVE | 持田製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |