Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469857 | 0.78 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL3074403 | 0.78 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL4956384 | 0.76 | CYP2A6 (0.69) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL31171 | 0.76 | CYP2A6 (0.69) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL16355131 | 0.76 | KDM4E (0.32) | HSD17B10ALDH1A1KDM4E | |
| SCHEMBL1109066 | 0.76 | CYP2A6 (0.48) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL12534737 | 0.74 | ALDH1A1 (0.58) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28807787 | 0.73 | CYP2A6 (0.65) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| Phosphine SCHEMBL27461872 | 0.73 | CYP2A6 (0.65) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| Water SCHEMBL29197442 | 0.73 | CYP2A6 (0.65) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303489-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2023-09-28 | — | — | US | disclosed |
| EP-3557998-B1 | COMPOUNS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2018119395-A1 | COMPOUNS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| EP-2677308-B1 | Method for fabricating large scale FET arrays | LIFE TECHNOLOGIES CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| CN-105254528-B | Synthesis of diamine monomer with azo and polyimide prepared from diamine monomer | 上海交通大学 | 2017-02-22 | — | — | CN | disclosed |
| EP-2674751-B1 | Apparatus for measuring analytes using large scale FET arrays | LIFE TECHNOLOGIES CORP (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2639579-B1 | Apparatus for measuring analytes using large scale FET arrays | LIFE TECHNOLOGIES CORP (US) | 2016-11-16 | — | — | EP | disclosed |
| EP-2639578-B1 | Apparatus for measuring analytes using large scale fet arrays | LIFE TECHNOLOGIES CORP (US) | 2016-09-14 | — | — | EP | disclosed |
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | SCRIPPS RESEARCH INST (US) | 2014-12-25 | — | — | US | disclosed |
| EP-2677309-B9 | Methods for sequencing a nucleic acid using large scale FET arrays, configured to measure a limited pH range | LIFE TECHNOLOGIES CORP (US) | 2014-11-19 | — | — | EP | disclosed |
| EP-2653861-B1 | Method for sequencing a nucleic acid using large-scale FET arrays | LIFE TECHNOLOGIES CORP (US) | 2014-08-13 | — | — | EP | disclosed |
| EP-2677309-B1 | Methods for sequencing a nucleic acid using large scale FET arrays, configured to measure a limited pH range | LIFE TECHNOLOGIES CORP (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8765920-B2 | Tyrosine bioconjugation through aqueous Ene-like reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120289682-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | THE SCRIPPS RESEARCH INSTITUTE | 2012-11-15 | — | — | US | disclosed |
| WO-2011079315-A1 | TYROSINE BIOCONJUGATION THROUGH AQUEOUS ENE-LIKE REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303489-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | FUS, TFEB, CLN6 | CYP2A6 4425/4885HSD17B10 3408/4885ALDH5A1 3578/4885 |
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | TYR, DNPEP, TH | CYP2A6 2178/4885HSD17B10 3715/4885ALDH5A1 2235/4885 |
| US-20120289682-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | TYR, DNPEP, TH | CYP2A6 2178/4885HSD17B10 3715/4885ALDH5A1 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.