Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632929 | 0.91 | RARA (0.46) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL2013985 | 0.91 | RARA (0.46) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL2013393 | 0.91 | RARA (0.46) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL12633167 | 0.90 | RARA (0.47) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL12959463 | 0.90 | HTR1A (0.45) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL31060378 | 0.88 | RARB (0.47) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL8513887 | 0.88 | RARB (0.47) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL2049463 | 0.88 | HTR1A (0.44) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL12633235 | 0.86 | HTR1A (0.43) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL12633016 | 0.86 | RARA (0.43) | HTR1ADRD2DRD4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072791-A1 | SPHINGOSINE KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2011-06-23 | — | — | WO | disclosed |