SCHEMBL1263271

SCHEMBL1263271

C=CC(=O)c1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27440604 0.89 MAPT (0.55)
SCHEMBL6994743 0.82 MAPT (0.69)
SCHEMBL6994738 0.82 MAPT (0.69)
SCHEMBL11334153 0.81 NPC1 (0.47)
SCHEMBL3165195 0.80
SCHEMBL7827549 0.78
SCHEMBL21843896 0.78
Water SCHEMBL10939261 0.78 CES2 (0.58)
SCHEMBL6199324 0.78
SCHEMBL3246325 0.77 MAPT (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650837-B Method for preparing ketone compound by 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2024-05-17 CN claimed
CN-115650837-A Method for preparing ketone compound by utilizing 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2023-01-31 CN claimed
CN-109837079-A A kind of high injection salt resistance polymers for oil recovery, three-component compound system and preparation method thereof 大庆再创科技有限公司 2019-06-04 CN claimed
US-9296656-B2 UV protective coatings INTERNATIONAL TECHNOLOGY CENTER (US) 2016-03-29 US claimed
WO-2012107488-A2 METAL-FREE PHOTOSENSITIZERS UNIVERSITA' DEGLI STUDI DI MILANO (IT) 2012-08-16 WO claimed
US-20090297828-A1 Uv protective coatings INTERNATIONAL TECHNOLOGY CENTER (US) 2009-12-03 US claimed
US-7612138-B2 coating material comprising an onion-like-carbon nanoparticles suspended in a binder; absorbing radiation in the frequency range of approximately 500MHz to 30 THz; use in electromagnetic Interference shielding structure INTERNATIONAL TECHNOLOGY CENTER (US) 2009-11-03 US claimed
US-20060241236-A1 Electromagnetic radiation attenuation KUZNETSOV VLADIMIR L 2006-10-26 US claimed
US-12365927-B2 Engineered ketoreductase polypeptides CODEXIS, INC. (US) 2025-07-22 US disclosed
CN-115650837-B Method for preparing ketone compound by 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2024-05-17 CN disclosed
CN-117945820-A Method for synthesizing alpha, beta-unsaturated aldehyde compound by copper catalysis 江苏海洋大学 2024-04-30 CN disclosed
CN-116745281-A Curing catalyst, resin composition, sealing material, adhesive, and cured product 纳美仕有限公司 2023-09-12 CN disclosed
US-20230104779-A1 ENGINEERED KETOREDUCTASE POLYPEPTIDES INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2023-04-06 US disclosed
CN-115650837-A Method for preparing ketone compound by utilizing 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2023-01-31 CN disclosed
US-20060241236-A1 Electromagnetic radiation attenuation KUZNETSOV VLADIMIR L 2006-10-26 US disclosed
EP-1670779-A2 METHODS FOR THE PRODUCTION OF 3-METHYLAMINO-1-(THIENE-2-YL)-PROPANE-1-OL BASF Aktiengesellschaft (DE) 2006-06-21 EP disclosed
WO-2005033094-A2 METHODS FOR THE PRODUCTION OF 3-METHYLAMINO-1-(THIENE-2-YL)-PROPANE-1-OL BASF AKTIENGESELLSCHAFT (DE) 2005-04-14 WO disclosed
EP-0630891-A1 3-Isothiazolones derivatives and their use as antimicrobial agents ROHM AND HAAS COMPANY (US) 1994-12-28 EP disclosed
US-5321141-A Reacting an isothiazole with an a,b-unsaturated ketone or aldehyde ROHM AND HAAS COMPANY (US) 1994-06-14 US disclosed
US-5288693-A Microbiocides ROHM AND HAAS COMPANY (US) 1994-02-22 US disclosed