Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12668273 | 0.94 | TSHR (0.41) | SMN1; SMN2ALDH1A1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL12057431 | 0.91 | TSHR (0.41) | MLNRNR1I2ESR1NR3C1PGR | |
| Hydrochloric Acid SCHEMBL584953 | 0.90 | CYP1A2 (0.40) | MLNRNR1I2ESR1NR3C1PGR | |
| SCHEMBL12633075 | 0.90 | TERT (0.43) | MLNRNR1I2ESR1NR3C1PGR | |
| SCHEMBL584884 | 0.88 | TSHR (0.47) | SMN1; SMN2CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL12668271 | 0.88 | THRA (0.43) | HTR1A | |
| SCHEMBL12057455 | 0.87 | TERT (0.43) | MLNRNR1I2ESR1NR3C1PGR | |
| SCHEMBL12057450 | 0.87 | TERT (0.43) | SMN1; SMN2ALDH1A1LMNACYP3A4HTT | |
| SCHEMBL12057400 | 0.87 | TERT (0.43) | SMN1; SMN2ALDH1A1LMNACYP3A4HTT | |
| SCHEMBL12057441 | 0.87 | TERT (0.43) | SMN1; SMN2ALDH1A1LMNACYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |