Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARA | P10276 | 3/20 | 0.44 |
| ▸ | PDE5A | O76074 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241245 | 0.98 | RARG (0.45) | RARGRARBRARAPDE5AKCNH2 | |
| SCHEMBL2014293 | 0.94 | RARG (0.44) | RARGRARBRARAPDE5AKCNH2 | |
| SCHEMBL12632960 | 0.82 | RARA (0.43) | RARGRARBRARAPDE5AKCNH2 | |
| SCHEMBL12633230 | 0.82 | RARB (0.39) | RARGRARBRARAPDE5AKCNH2 | |
| SCHEMBL2016394 | 0.81 | RARG (0.45) | RARGRARBRARAPDE5ADRD2 | |
| SCHEMBL15241246 | 0.81 | RARB (0.39) | RARGRARBRARAPDE5AKCNH2 | |
| SCHEMBL2016809 | 0.79 | ACHE (0.39) | RARGRARBRARADRD2 | |
| SCHEMBL12633904 | 0.79 | CKS1B (0.42) | RARGRARBRARARXRA | |
| SCHEMBL2015010 | 0.78 | RARG (0.43) | RARGRARBRARAPDE5ADRD2 | |
| SCHEMBL2012292 | 0.78 | ACHE (0.40) | RARGRARBRARADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072791-A1 | SPHINGOSINE KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2011-06-23 | — | — | WO | disclosed |