Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LOX | P28300 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635612 | 0.87 | DRD2 (0.49) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL12636531 | 0.83 | MEN1 (0.49) | MEN1KMT2AABL1KCNH2LMNA | |
| SCHEMBL12635603 | 0.82 | HTT (0.54) | LMNAMAPTALDH1A1NPSR1HSD17B10 | |
| SCHEMBL15676725 | 0.74 | MEN1 (0.71) | MEN1KMT2ALMNAPOLBCTDSP1 | |
| SCHEMBL12636160 | 0.73 | KMT2A (0.63) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL1696431 | 0.72 | MEN1 (0.68) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL18330540 | 0.72 | KMT2A (0.68) | MEN1KMT2ALMNAMAPTPOLB | |
| SCHEMBL6014761 | 0.72 | NPC1 (0.67) | MEN1KMT2AARNPC1RAB9A | |
| SCHEMBL12636174 | 0.71 | SLC7A5 (0.51) | KMT2AMAPTALDH1A1POLB | |
| SCHEMBL12634650 | 0.71 | MAPK14 (0.47) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |