Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635653 | 0.91 | PPARG (0.49) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12635621 | 0.89 | PTGER4 (0.49) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12635616 | 0.89 | PTGER4 (0.49) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12634630 | 0.88 | PPARA (0.59) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12635633 | 0.86 | LIPG (0.51) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12636180 | 0.85 | LIPG (0.53) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12635622 | 0.84 | PTGER4 (0.46) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12635638 | 0.84 | LIPG (0.51) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12634656 | 0.83 | LIPG (0.52) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL12636549 | 0.82 | PPARA (0.51) | PTGER4PTGER2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |