Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635633 | 0.89 | LIPG (0.51) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12635638 | 0.88 | LIPG (0.51) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12636180 | 0.88 | LIPG (0.53) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12634630 | 0.87 | PPARA (0.59) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12636183 | 0.86 | LMNA (0.50) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12635616 | 0.84 | PTGER4 (0.49) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12635621 | 0.84 | PTGER4 (0.49) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12635653 | 0.83 | PPARG (0.49) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12635656 | 0.83 | PTGER4 (0.50) | LIPGPPARGPPARDPPARAPTGER4 | |
| SCHEMBL12634650 | 0.82 | MAPK14 (0.47) | LIPGPTGER4PTGER2CYP3A4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |