SCHEMBL126360

SCHEMBL126360

c1cc(-c2cccc3ccccc23)cc(-c2c3ccccc3c(-c3ccc4cc(-c5cccc6c5oc5ccccc56)ccc4c3)c3ccccc23)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.54
GGPS1 O95749 1/20 0.44
PRKDC P78527 4/20 0.41
PTGES2 Q9H7Z7 1/20 0.41
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MCL1 Q07820 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15195402 0.96 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL12577497 0.95 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL12577501 0.95 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL126541 0.95 ALOX5 (0.54) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL126764 0.95 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL29988532 0.95 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL126788 0.95 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL126439 0.94 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL126276 0.94 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL125809 0.94 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301175-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20230301175-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20220223793-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2022-07-14 US disclosed
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-01-27 US disclosed
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2021-06-01 US disclosed
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-08-13 US disclosed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US disclosed
US-10566541-B2 Aromatic amine derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US disclosed
US-10388885-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2019-08-20 US disclosed
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885GGPS1 4618/4885PRKDC 4722/4885
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885GGPS1 4618/4885PRKDC 4722/4885
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 ALOX5 3902/4885GGPS1 4441/4885PRKDC 4824/4885
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 ALOX5 3494/4885GGPS1 4695/4885PRKDC 4771/4885
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885GGPS1 4618/4885PRKDC 4722/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 ALOX5 4030/4885GGPS1 4552/4885PRKDC 4807/4885
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885GGPS1 4618/4885PRKDC 4722/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885GGPS1 4618/4885PRKDC 4722/4885
US-20220223793-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, DRD1 ALOX5 358/4885GGPS1 1055/4885PRKDC 2097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.