SCHEMBL12636741

SCHEMBL12636741

Cc1cn(C)c(C)c1/N=N/c1c(C(C)(C)C)nn(-c2ccccc2)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 12/20 0.49
SMN1; SMN2 Q16637 12/20 0.49
MAPT P10636 11/20 0.49
NPC1 O15118 11/20 0.49
TDP1 Q9NUW8 6/20 0.49
HPGD P15428 5/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPK1 P28482 7/20 0.46
LMNA P02545 5/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NFKB1 P19838 4/20 0.46
NFKB2 Q00653 4/20 0.46
RELA Q04206 4/20 0.46
PLA2G1B P04054 2/20 0.45
ATG4B Q9Y4P1 2/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALOX12 P18054 1/20 0.44
HTT P42858 1/20 0.44
GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12636743 0.91 RAB9A (0.47) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL12636744 0.80 CCNT1 (0.36) POLB
SCHEMBL12636761 0.75 RAB9A (0.46) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL15958244 0.74 RAB9A (0.44) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL12636700 0.74 GAA (0.44) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL92470 0.74 RAB9A (0.42) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL91890 0.72 SMN1; SMN2 (0.51) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL92402 0.72 MAPT (0.50) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL2623686 0.72 SMN1; SMN2 (0.51) RAB9ASMN1; SMN2MAPTNPC1TDP1
SCHEMBL12636709 0.71 GAA (0.46) RAB9ASMN1; SMN2MAPTNPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947625-B2 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-20070202282-A1 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed