SCHEMBL92402

SCHEMBL92402

CC(C)(C)c1nn(-c2ccccc2)c(N)c1N=Nc1ccc(C#N)c(C#N)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.50
RAB9A P51151 10/20 0.50
NPC1 O15118 9/20 0.50
SMN1; SMN2 Q16637 9/20 0.50
TDP1 Q9NUW8 6/20 0.50
MAPK1 P28482 6/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 5/20 0.48
NFKB1 P19838 4/20 0.48
NFKB2 Q00653 4/20 0.48
RELA Q04206 4/20 0.48
HPGD P15428 3/20 0.48
ALDH1A1 P00352 1/20 0.48
PLA2G1B P04054 2/20 0.47
ATG4B Q9Y4P1 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
ALOX12 P18054 1/20 0.46
HTT P42858 1/20 0.46
ATM Q13315 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13850052 0.80 MAOA (0.39) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL12636762 0.80 MAPT (0.40) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL12636700 0.77 GAA (0.44) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL14534964 0.76 ALOX5 (0.35) MAPTSMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL10106113 0.76 GAA (0.43) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL2623686 0.76 SMN1; SMN2 (0.51) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL91890 0.76 SMN1; SMN2 (0.51) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL12636709 0.74 GAA (0.46) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL12636726 0.74 MAPT (0.41) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL12636701 0.73 GAA (0.45) MAPTRAB9ANPC1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129309-B2 Multilayer; substrate with at least three heat sensitive transfer sheets containing dyes and resins, heat resistant slipping layers; containing polyvinyl butyral and polyvinyl acetate FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8119562-B2 Heat-sensitive transfer sheet and image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8067336-B2 Polyethylene innermost surface layer FUJIFILM CORPORATION (JP) 2011-11-29 US disclosed
US-8017552-B2 Has thermal transfer layer on a support, can stably keep up good capability of peeling off an image-receiving sheet without being affected by properties of a support, running stability FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-8012909-B2 Receiver sheet includes receptor layer containing yellow, cyan, magenta dyes; superimposing heat sensitive transfer sheet ; heating; process control FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7932210-B2 Image-forming method using thermal transfer system FUJIFILM CORPORATION (JP) 2011-04-26 US disclosed
US-7879524-B2 Heat sensitive transfer image receiver sheet and heat sensitive transfer sheet on support; dye receiver layer; heat insulation layer containing hollow polymer particles and hydrophilic polymer FUJIFILM CORPORATION (JP) 2011-02-01 US disclosed
US-20090196141-A1 OPTICAL RECORDING MEDIUM, METHOD FOR UTILIZING DYE COMPOUND AND VISIBLE INFORMATION RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 US disclosed
US-20080287291-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080274881-A1 THERMOSENSITIVE TRANSFER INK SHEET, AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080274880-A1 HEAT-SENSITIVE TRANSFER SHEET FOR USE IN HEAT-SENSITIVE TRANSFER SYSTEM AND IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080269048-A1 CARDBOARD CYLINDER FOR A HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET, ROLLED HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET TO FORM A ROLL SHAPE, AND IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080254383-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080254981-A1 HEAT-SENSITIVE TRANSFER IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080248949-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMATION METHOD FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed
US-20080081766-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
US-20070213217-A1 Image-forming method using thermal transfer system FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed