SCHEMBL12636769

SCHEMBL12636769

Cc1csc(/N=N/c2c(-c3ccccc3)nn(C)c2N)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
MAPT P10636 9/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
KMT2A Q03164 4/20 0.37
MAPK1 P28482 3/20 0.37
MEN1 O00255 3/20 0.37
HSD17B10 Q99714 2/20 0.37
CASP1 P29466 1/20 0.37
BRCA1 P38398 1/20 0.37
HTT P42858 1/20 0.37
CASP7 P55210 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MGAM O43451 2/20 0.36
GAA P10253 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12636767 0.78 MAPT (0.54) MAPTSMN1; SMN2ALDH1A1HPGDKMT2A
SCHEMBL12636742 0.76 MAPT (0.51) CA1CA2MAPTSMN1; SMN2ALDH1A1
SCHEMBL5201246 0.71 MAPT (0.47) CA1CA2MAPTSMN1; SMN2ALDH1A1
SCHEMBL2211852 0.70 ALDH1A1 (0.46) MAPTSMN1; SMN2ALDH1A1HPGDKMT2A
SCHEMBL2211854 0.70 ALDH1A1 (0.46) MAPTSMN1; SMN2ALDH1A1HPGDKMT2A
SCHEMBL12636737 0.69 POLB (0.43) CA1CA2MAPTSMN1; SMN2ALDH1A1
SCHEMBL12636694 0.69 TDP1 (0.45) CA1CA2MAPTALDH1A1ADORA2A
SCHEMBL4214390 0.67 MAPT (0.58) MAPTSMN1; SMN2ALDH1A1HPGDADORA2A
SCHEMBL824840 0.67 MAPT (0.35) CA1CA2MAPTSMN1; SMN2ALDH1A1
SCHEMBL33804 0.66 MAPT (0.55) MAPTSMN1; SMN2ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947625-B2 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-7947625-B2 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-20070202282-A1 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed
US-20070202282-A1 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed